FlyBase Allele Report: Dmel\kibra[KK111409]

General Information

Symbol

Dmel\kibra^KK111409

Species

D. melanogaster

Name

FlyBase ID

FBal0237408

Feature type

allele

Associated gene

Dmel\kibra

Associated Insertion(s)

Carried in Construct

P{KK111409}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK111409}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK111409

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^en-e16E

(Poon et al., 2011)

visible | adult stage, with Scer\GAL4^en-e16E

(Poon et al., 2011)

visible | adult stage, with Scer\GAL4^nub-AC-62

(Sabarís et al., 2025)

Phenotype Manifest In

wing, with Scer\GAL4^en-e16E

(Poon et al., 2011)

wing, with Scer\GAL4^nub-AC-62

(Sabarís et al., 2025)

wing vein | ectopic, with Scer\GAL4^nub-AC-62

(Sabarís et al., 2025)

Detailed Description

Statement

Reference

Expression of kibra^KK111409 under the control of Scer\GAL4^en-e16E results in wing overgrowth.

(Poon et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, kibra^KK111409 has abnormal size | adult stage phenotype, enhanceable by Tao⁵⁰

(Poon et al., 2011)

Scer\GAL4^en-e16E, kibra^KK111409 has visible | adult stage phenotype, enhanceable by Tao⁵⁰

(Poon et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, kibra^KK111409 has abnormal size | adult stage phenotype, suppressible by Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG}

(Poon et al., 2011)

Scer\GAL4^en-e16E, kibra^KK111409 has visible | adult stage phenotype, suppressible by Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG}

(Poon et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

kibra^KK111409 has wing phenotype, enhanceable by Tao⁵⁰

(Poon et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, kibra^KK111409 has wing phenotype, suppressible by Scer\GAL4^en-e16E/Tao^{UASp.Tag:FLAG}

(Poon et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Tao⁵⁰ enhances the increase in wing size seen when kibra^KK111409 is expressed under the control of Scer\GAL4^en-e16E.

Expression of Tao^{Scer\UAS.P\T.T:Zzzz\FLAG} reduces the wing overgrowth seen when kibra^KK111409 is expressed under the control of Scer\GAL4^en-e16E.

(Poon et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v106507

P{KK111409}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG33967^KK111409

kibra^KK111409

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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