FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tao50
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General Information
Symbol
Dmel\Tao50
Species
D. melanogaster
Name
FlyBase ID
FBal0265905
Feature type
allele
Associated gene
Dmel\Tao
Associated Insertion(s)
Carried in Construct
Also Known As
Tao-150
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(King et al., 2011)
Mutagen
Delta2-3 transposase
(King et al., 2011)
Progenitor genotype
Cytology
Description

Imprecise excision of the P{EP} element in P{EP}TaoEP1455 resulted in a 2077bp deletion from 753bp upstream to 1324bp downstream of the Tao start D and E transcript start site. Tao50 also contains 4 smaller deletions at the following positions upstream relative to the Tao transcription site: 2301-2312 (12bp), 2294-2299 (5bp), 902-905 (3bp) and 882-900 (18bp).

(King et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:19,578,484..19,580,561 [-]
Comment:

Imprecise excision of P{EP}TaoEP1455 resulted in a 2077bp deletion from 753bp upstream to 1324bp downstream of the Tao transcription start site, which was reported as X:19473841 in r5 coordinates. Tao50 also contains four smaller upstream deletions at the following positions upstream relative to the tao transcription start site: 2301в313 (12 bp), 2294 в299 (5 bp), 902й05 (3 bp), and 882й00 (18 bp).

(King et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous female Tao50 mutants exhibit similar levels of ethanol-induced hyperactivity to wild type.

      TaoEP1455/Tao50 males exhibit greatly diminished ethanol-induced hyperactivity compared to wild type.

      (King et al., 2011)

      The wings of Tao50/TaoEP1455 mutant flies are 8% larger than controls.

      (Poon et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Suppressor of
      Statement
      Reference

      Tao50 is a suppressor of visible phenotype of Scer\GAL432B, ftΔECD.UAS

      (Poon et al., 2011)

      Tao50 is a suppressor of abnormal size phenotype of Scer\GAL432B, ftΔECD.UAS

      (Poon et al., 2011)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Tao50 is an enhancer of wing | posterior phenotype of Scer\GAL4en-e16E, hpoRNAi.UAS.cPa

      (Poon et al., 2011)

      Tao50 is an enhancer of wing phenotype of kibraKK111409

      (Poon et al., 2011)
      Suppressor of
      Statement
      Reference

      Tao50 is a suppressor of wing phenotype of Scer\GAL432B, ftΔECD.UAS

      (Poon et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Tao50 enhances the increase in wing size seen when kibraKK111409 is expressed under the control of Scer\GAL4en-e16E.

      Tao50 enhances the increase in wing size seen when hpodsRNA.Scer\UAS is expressed under the control of Scer\GAL4en-e16E.

      Tao50 suppresses the reduced wing size phenotype seen when ftΔECD.Scer\UAS is expressed under the control of Scer\GAL432B.

      (Poon et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Tao-150
      (Boggiano et al., 2011, Poon et al., 2011)
      Tao50
      tao50
      (Pflanz et al., 2015, King et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)