FlyBase Allele Report: Dmel\ci[75.UAS]

General Information

Symbol

Dmel\ci^75.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0239071

Feature type

allele

Associated gene

Dmel\ci

Associated Insertion(s)

Carried in Construct

P{UAS-ci.75}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Mosimann et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-ci.75}

Cytology

Description

UAS regulatory sequences drive expression of the ci75 form of ci.

(Mosimann et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^C-765

(Mosimann et al., 2009)

visible, with Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Phenotype Manifest In

wing blade, with Scer\GAL4^C-765

(Mosimann et al., 2009)

wing blade, with Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Detailed Description

Statement

Reference

Expression of ci^75.Scer\UAS with the pan-wing disc driver Scer\GAL4^C-765 or the stronger Scer\GAL4^nub-AC-62 driver results in an extensive ablation of the anterior compartment and a severe reduction of the posterior wing blade area.

(Mosimann et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^C-765, ci^75.UAS has visible phenotype, suppressible | partially by hyx^UAS.cMa/Scer\GAL4^C-765

(Mosimann et al., 2009)

Scer\GAL4^C-765, ci^75.UAS has visible phenotype, suppressible | partially by Scer\GAL4^C-765/hyx^EP9

(Mosimann et al., 2009)

Scer\GAL4^nub-AC-62, ci^75.UAS has visible phenotype, suppressible | partially by hyx^UAS.cMa/Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Scer\GAL4^nub-AC-62, ci^75.UAS has visible phenotype, suppressible | partially by Hsap\CDC73^UAS.cMa, Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^C-765, ci^75.UAS has wing blade phenotype, suppressible | partially by hyx^UAS.cMa/Scer\GAL4^C-765

(Mosimann et al., 2009)

Scer\GAL4^C-765, ci^75.UAS has wing blade phenotype, suppressible | partially by Scer\GAL4^C-765/hyx^EP9

(Mosimann et al., 2009)

Scer\GAL4^nub-AC-62, ci^75.UAS has wing blade phenotype, suppressible | partially by hyx^UAS.cMa/Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Scer\GAL4^nub-AC-62, ci^75.UAS has wing blade phenotype, suppressible | partially by Hsap\CDC73^UAS.cMa, Scer\GAL4^nub-AC-62

(Mosimann et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of either hyx^Scer\UAS.cMa or hyx^EP9 with Scer\GAL4^C-765 driven ci^75.Scer\UAS leads to a striking, albeit incomplete, reversion to wild-type wing morphology. The wings recovered from such crosses often develop extra vein material anterior to wing vein L3, and wing basal cell 1 is never fully restored.

Co-expression of hyx^Scer\UAS.cMa with Scer\GAL4^nub-AC-62 driven ci^75.Scer\UAS leads to a striking, albeit incomplete, reversion to wild-type wing morphology.

(Mosimann et al., 2009)

Xenogenetic Interactions

Statement

Reference

Co-expression of Hsap\CDC73^Scer\UAS.cMa with Scer\GAL4^nub-AC-62 driven ci^75.Scer\UAS leads to a striking, albeit incomplete, reversion to wild-type wing morphology.

(Mosimann et al., 2009)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ci^75.Scer\UAS

ci^75.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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