FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mps1B8
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General Information
Symbol
Dmel\Mps1B8
Species
D. melanogaster
Name
FlyBase ID
FBal0239195
Feature type
allele
Associated gene
Dmel\Mps1
Associated Insertion(s)
Doc{}altB8
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Doc{}altB8
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        Mps1ald-1

        (Page et al., 2007)
        Rescued by

        Mps1B8 is rescued by Mps1+t4.2

        (Page et al., 2007)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Although the Doc{}altB8 insertion is within alt, evidence suggests that the mutant phenotype caused by the insertion is due to an effect on the upstream gene, ald, and not due to an effect on alt; the Doc{}altB8 chromosome fails to complement ald1 and is rescued by ald+t4.2, and altexcision18 (a mutation affecting only alt) complements the meiotic nondisjunction phenotype of the Doc{}altB8 chromosome.

        (Page et al., 2007)

        Associated with: altB8.

        (Page et al., 2007)

        FlyBase curator comment: two alleles are associated with Doc{}altB8 in the database; altB8, which represents the insertion within the alt transcription unit, and aldB8, which represents the mutant phenotype caused by the effect of the insertion on the ald gene.

        (Page et al., 2007)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Mps1B8
        aldB8
        (Page et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)