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General Information
Symbol
Dmel\NJF02959
Species
D. melanogaster
Name
FlyBase ID
FBal0239461
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of NJF02959 under the control of Scer\GAL4tj-NP1624 leads to fusion of follicles in the ovary, a significant reduction in the average number of cap cells per germarium, and a significant decrease in the average number of germline stem cells per germarium, but no significant change in the number of terminal filament cells. In some cases, all cap cells and germline stem cells are missing, and escort cells are misplaced to the tip of the germarium, where they make contact with the terminal filament and a differentiating germline cyst.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT suppressed by
Suppressor of
Other
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of tjScer\UAS.cGa fails to suppress the decrease in cap cell and germline stem cell numbers in ovaries from flies expressing NJF02959 under the control of Scer\GAL4tj-NP1624.

Terminal filaments in ovaries from flies expressing tjNIG.10034R and NJF02959 under the control of Scer\GAL4tj-NP1624 are considerably shorter than those from flies expressing only tjNIG.10034R, although on average are still significantly longer than those in controls. Ovaries from flies expressing tjNIG.10034R and NJF02959 have a significant decrease in the number of terminal filaments, and some terminal filaments are unusually short with fewer than 7 cells.

Xenogenetic Interactions
Statement
Reference

The aggressive tissue overgrowth observed in third instar larval wing discs carrying somatic (flip-out) clones simultaneously expressing Snr1HMS00363 and BacA\p35Scer\UAS.cHa driven by Scer\GAL4Act.PU is significantly suppressed by co-expression of NJF02959.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (11)