FB2026_02 , released June 18, 2026
Allele: Dmel\GyfHM05106
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General Information
Symbol
Dmel\GyfHM05106
Species
D. melanogaster
Name
FlyBase ID
FBal0240236
Feature type
allele
Associated gene
Dmel\Gyf
Associated Insertion(s)
Carried in Construct
P{TRiP.HM05106}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HM05106}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HM05106
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of GyfHM05106 under the control of Scer\GAL4GMR.PU has no effect on eye development and morphology.

      Expression of GyfHM05106 under the control of Scer\GAL4GMR.PU does not suppress apoptosis in the larval eye disc.

      (Kim et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4GMR.PU, GyfHM05106 is a suppressor | partially of eye phenotype of Atg13UAS.EGFP, Atg1UAS.Tag:MYC, Scer\GAL4GMR.PU

      (Kim et al., 2015)
      NOT Suppressor of
      Statement
      Reference

      GyfHM05106/Scer\GAL4Mef2.PR is a non-suppressor of mitochondrion | adult stage phenotype of Pink1B9

      (Ham et al., 2021)

      GyfHM05106/Scer\GAL4Mef2.PR is a non-suppressor of flight muscle cell | adult stage phenotype of Pink1B9

      (Ham et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of GyfHM05106 dramatically suppresses the eye degeneration and eye disc cell death seen when Atg1Scer\UAS.T:Hsap\MYC and Atg13Scer\UAS.T:Avic\GFP-EGFP are co-expressed under the control of Scer\GAL4GMR.PU at 18[o]C. However, the photoreceptor morphology is not fully restored. The increased autophagic flux in eye discs is also suppressed.

      (Kim et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG11148HM05106
      GyfHM05106
      Name Synonyms
      Secondary FlyBase IDs
        References (4)