FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\norpAUAS.ckb
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General Information
Symbol
Dmel\norpAUAS.ckb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Kwon
FlyBase ID
FBal0240387
Feature type
allele
Associated gene
Dmel\norpA
Associated Insertion(s)
Carried in Construct
P{UAS-norpA.WT}
Also Known As
UAS-norpA
Key Links
Transgenic product class
wild_type
(Kwon et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Kwon et al., 2008)
Mutagen
in vitro construct
(Kwon et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-norpA.WT}
Cytology
Description

UAS regulatory sequences drive expression of norpA coding sequences.

(Kwon et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
norpA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There is a modest but statisitically significant increase in 18[o]C preference when norpAScer\UAS.ckb is overexpressed (under the control of Scer\GAL4TrpA1.PR) in a wild-type background.

      (Kwon et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The thermotactic preference for 18[o]C in norpAScer\UAS.ckb; Scer\GAL4TrpA1.PR larvae is suppressed in a TrpA11 heterozygous background.

      (Kwon et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      norpAUAS.ckb/Scer\GAL4TrpA1-AB-G4 rescues norpAP24

      (Kim et al., 2010)

      norpAUAS.ckb/Scer\GAL4TrpA1.PR rescues norpAP24

      (Kwon et al., 2010)

      norpAUAS.ckb/Scer\GAL4Orco.2.642.Hsim\VP22 rescues norpAP24

      (Kwon et al., 2010)

      norpAUAS.ckb/Scer\GAL4TrpA1.PR rescues norpAP24

      (Kwon et al., 2008)
      Comments

      Expression of norpAScer\UAS.ckb using Scer\GAL4TrpA1-GAL4 rescues the reduced avoidance to aristolochic acid and the reduced aristolochic acid-induced action potentials shown by norpA36 mutants.

      (Kim et al., 2010)

      Expression of norpAScer\UAS.ckb under the control of either Scer\GAL4TrpA1.PR or Scer\GAL4Orco.2.642.T:Hsim\VP22 rescues the reduced avoidance to citronellal which is seen in norpA36 flies in a direct airborne repellent test (DART) assay.

      (Kwon et al., 2010)

      The presence of norpAScer\UAS.ckb, under the control of Scer\GAL4TrpA1.PR iresotred 18[o]C selection in norpA36 mutants.

      (Kwon et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      norpAScer\UAS.ckb
      norpAUAS.ckb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Kwon
      Secondary FlyBase IDs
        References (8)