FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Alkf01491
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General Information
Symbol
Dmel\Alkf01491
Species
D. melanogaster
Name
FlyBase ID
FBal0240575
Feature type
allele
Associated gene
Dmel\Alk
Associated Insertion(s)
PBac{WH}Alkf01491
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{WH}Alkf01491
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    PBac{WH}
    Regulatory region(s)
    UAS
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Alkts/Alkf01491 animals reared for 48 hours at 18[o]C and then subsequently shifted to 25[o]C show a strong increase (2.4-fold) in the mean excitatory junctional current (EJC) amplitude compared to controls.

        (Rohrbough et al., 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Alkf01491 is rescued by Scer\GAL4how-24B/Alkf01491

        (Rohrbough et al., 2013)
        Rescues

        Scer\GAL4how-24B/Alkf01491 rescues Alkf01491

        (Rohrbough et al., 2013)
        Comments

        Overexpression of Alk from the Scer\UAS regulatory sequences in the PBac{WH}Alkf01491 insertion rescues the increased mean excitatory junctional current amplitude seen in Alkts/Alkf01491 animals reared for 48 hours at 18[o]C and then subsequently shifted to 25[o]C.

        (Rohrbough et al., 2013)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        Alkf01491
        Alkf01491a
        Alkf01491b
        alkf01491
        (Rohrbough et al., 2013)
        Name Synonyms
        Secondary FlyBase IDs
        • FBal0223332
        • FBal0223333
        References (3)