FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\paraunspecified
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General Information
Symbol
Dmel\paraunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0240905
Feature type
allele
Associated gene
Dmel\para
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 1 )
        Disease
        Evidence
        References
        model of  epilepsy
        CEA
        (Kuebler and Tanouye, 2002)
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Flies have a lower seizure threshold on exposure to high frequency electrical stimuli compared to wild type. Seizures induced by a single HFS stimulus of 40V can be completely suppressed by 25mM valproate.

        (Kuebler and Tanouye, 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT suppressed by
        Statement
        Reference

        paraunspecified has bang sensitive | recessive phenotype, non-suppressible by Top1JS

        (Song et al., 2007)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The bang sensitive phenotype and decreased seizure threshold of bssunspecified is not suppressed by Top1JS/Y, however, the increased recovery time after seizure seen in these flies is partially suppressed by Top1JS/Y.

        (Song et al., 2007)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        bssunspecified
        paraunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (4)