FlyBase Allele Report: Dmel\tal[pri-2]

General Information

Symbol

Dmel\tal^pri-2

Species

D. melanogaster

Name

FlyBase ID

FBal0241051

Feature type

allele

Associated gene

tal

Associated Insertion(s)

Carried in Construct

Also Known As

pri²

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

FLPase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Kondo et al., 2007)

Mutagen

FLPase

(Kondo et al., 2007)

Progenitor genotype

P{XP}d06750

(Kondo et al., 2007)

PBac{WH}f04098

(Kondo et al., 2007)

Cytology

Description

Recombination between the two progenitor insertions has resulted in a deletion that removes the entire tal transcription unit.

(Kondo et al., 2007)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3R:13,812,893..13,818,070 [+]

Comment:

Estimated endpoints of a deletion resulting from FLP-catalyzed recombination using the FRT-containing transposons P{XP}d06750 and PBac{WH}f04098.

(Kondo et al., 2007)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Kondo et al., 2007)

some die during embryonic stage | recessive

(Kondo et al., 2007)

Phenotype Manifest In

cephalopharyngeal skeleton (with tal^pri-1)

(Kondo et al., 2007)

embryonic/larval posterior spiracle (with tal^pri-1)

(Kondo et al., 2007)

larval dorsal hair (with tal^pri-1)

(Kondo et al., 2007)

taenidial fold (with tal^pri-1)

(Kondo et al., 2007)

ventral denticle belt (with tal^pri-1)

(Kondo et al., 2007)

Detailed Description

Statement

Reference

tal^pri-1/tal^pri-2 embryos show a number of cuticle phenotypes; they completely lack denticle belts and dorsal hairs, and the head skeleton and posterior spiracles are deformed. The mutant embryos lack the specific F-actin accumulation that is normally seen at the site of denticle formation, but the F-actin signal at the cell boundaries remains in the presumptive denticle cells.

tal^pri-1/tal^pri-2 embryos lack the taenidial folds in the tracheal system.

(Kondo et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

tal^pri-2/tal^pri-1 is rescued by Scer\GAL4^arm.PS/tal^ORF1.UAS

(Kondo et al., 2007)

tal^pri-2/tal^pri-1 is rescued by tal^ORF3.UAS/Scer\GAL4^arm.PS

(Kondo et al., 2007)

tal^pri-2/tal^pri-1 is rescued by tal^ORF4.UAS/Scer\GAL4^arm.PS

(Kondo et al., 2007)

Not rescued by

tal^pri-2/tal^pri-1 is not rescued by Scer\GAL4^arm.PS/tal^1-4FS.UAS

(Kondo et al., 2007)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

pri²

(Öztürk-Çolak et al., 2016, Kondo et al., 2007)

tal^pri-2

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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