FB2026_02 , released June 18, 2026
Allele: Dmel\pyrc02915a
Open Close
General Information
Symbol
Dmel\pyrc02915a
Species
D. melanogaster
Name
FlyBase ID
FBal0241058
Feature type
allele
Associated gene
Dmel\pyr
Associated Insertion(s)
PBac{PB}pyrc02915a
Carried in Construct
Also Known As
pyr02915
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{PB}pyrc02915a
    Cytology
    Description

    Insertion in the first intron.

    (Kadam et al., 2009)
    Allele components
    Component
    Use(s)
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        pyrc02915a mutants have a 50% reduction in glial cell number in the eye disc compared to controls.

        (Franzdóttir et al., 2009)

        Homozygous embryos show defects in mesoderm spreading during stage 8, which results in the mesoderm forming a multilayered structure at stages 9-10 (in contrast to wild-type embryos where the mesoderm forms a single layer of cells at this stage).

        Stage 14 homozygous embryos have gaps within the row of heart progenitors at stage 14.

        (Kadam et al., 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        pyr18

        (Klingseisen et al., 2009)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        pyr02915
        (Avet-Rochex et al., 2012, Knox et al., 2011, Kadam et al., 2009, Klingseisen et al., 2009)
        pyrC02915a
        (Knox et al., 2011)
        pyrP02915
        pyrc02915a
        (Franzdóttir et al., 2009)
        Name Synonyms
        Secondary FlyBase IDs
        • FBal0222965
        • FBal0239035
        References (6)