FB2026_02 , released June 18, 2026
Allele: Dmel\PldK1086R.UAS
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General Information
Symbol
Dmel\PldK1086R.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0241090
Feature type
allele
Associated gene
Dmel\Pld
Associated Insertion(s)
Carried in Construct
P{UAS-Pld.K1086R}
Key Links
Transgenic product class
missense_variant
(Raghu et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Raghu et al., 2009)
Mutagen
in vitro construct
(Raghu et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Pld.K1086R}
Cytology
Description

Amino acid replacement: K1086R.

(Raghu et al., 2009)

UASt regulatory sequences drive expression of a catalytically dead form of Pld.

(Raghu et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Pld
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of PldScer\UAS.cRa under the control of Scer\GAL4ninaE.PU results has no significant effect on the number of rhodopsin1-containing vesicles per ommatidium upon illumination, which as in wild-type slightly increases compared to pre-illumination.

      (Thakur et al., 2016)

      Flies expressing PldK1086R.Scer\UAS under the control of Scer\GAL4GMR.PF do not show defects in the photoreceptors.

      Retinal extracts from flies expressing PldK1086R.Scer\UAS under the control of Scer\GAL4GMR.PF have a normal phospholipid profile.

      (Raghu et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4hs.PU/PldK1086R.UAS fails to rescue Pld3.1

      (Thakur et al., 2016)
      Comments

      The light-dependent retinal regeneration observed in Pld3.1 homozygous adults cannot be rescued by expression of PldK1086R.Scer\UAS under the control of Scer\GAL4hs.PU in the mutant background.

      (Thakur et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PldK1086R.Scer\UAS
      PldK1086R.UAS
      dPLDK/R
      (Thakur et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)