FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\eEF1γS294A.UAS
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General Information
Symbol
Dmel\eEF1γS294A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0241767
Feature type
allele
Associated gene
Dmel\eEF1γ
Associated Insertion(s)
Carried in Construct
P{UAS-eEF1γ.S294A}
Key Links
Transgenic product class
missense_variant
(Fan et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Fan et al., 2010)
Mutagen
in vitro construct
(Fan et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-eEF1γ.S294A}
Cytology
Description

Amino acid replacement: S294A.

(Fan et al., 2010)

UAS regulatory sequences drive expression of a mutated form of eEF1γ cDNA.

(Fan et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
eEF1γ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Ef1γS294A.Scer\UAS under the control of Scer\GAL4GMR.PF results in a slight rough eye phenotype, with occasional fused facets.

      (Fan et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4da.G32/eEF1γS294A.UAS partially rescues eEF1γA70

      (Fan et al., 2010)
      Comments

      Expression of Ef1γScer\UAS.cFa under the control of Scer\GAL4da.G32 rescues the lethality of Ef1γA70 males, but only poorly rescues the lethality of Ef1γA70 females.

      (Fan et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ef1γS294A.Scer\UAS
      eEF1γS294A.Scer\UAS
      eEF1γS294A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)