FlyBase Allele Report: Dmel\eEF1γ[A70]

General Information

Symbol

Dmel\eEF1γ^A70

Species

D. melanogaster

Name

FlyBase ID

FBal0192923

Feature type

allele

Associated gene

Dmel\eEF1γ

Associated Insertion(s)

P{?EP}eEF1γ^A70

Carried in Construct

Also Known As

Ef1γ^A70

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Fan et al., 2010)

Progenitor genotype

P{EP}eEF1γ^GE29510

(Fan et al., 2010)

Associated Insertion(s)

P{?EP}eEF1γ^A70

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a 662bp deletion that removes the 5' third of Ef1γ, including the translation start site. 21bp of the original insertion remain.

(Fan et al., 2010)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3R:29,220,167..29,220,828 [+]

Comment:

A 662 bp deletion associated with the imprecise excision of P{EP}eEF1gamma^GE29510. 21 bp of the P element remain at the site of the excision.

Inserted_sequence:

CATGATGAAATAACATCCTGC

(Fan et al., 2010)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

EF192542

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | recessive | somatic clone

(Fan et al., 2010)

lethal (with Df(3R)Exel6212)

(Fan et al., 2010)

lethal (with eEF1γ^GE29510)

(Fan et al., 2010)

lethal - all die before end of larval stage | recessive

(Fan et al., 2010)

some die during larval stage | recessive

(Fan et al., 2010)

visible | adult stage | dominant

(Jejina et al., 2024)

Phenotype Manifest In

eye | somatic clone

(Fan et al., 2010)

posterior scutellar bristle

(Jejina et al., 2024)

Detailed Description

Statement

Reference

Homozygous clones are not recovered in the adult eye.

(Fan et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

BicD^r, eEF1γ^A70 has visible | adult stage phenotype

(Jejina et al., 2024)

BicDR⁷¹, BicD^r, eEF1γ^A70 has visible | adult stage phenotype

(Jejina et al., 2024)

BicDR⁷¹, eEF1γ^A70 has visible | adult stage phenotype

(Jejina et al., 2024)

Phenotype Manifest In

Other

Statement

Reference

BicD^r, eEF1γ^A70 has macrochaeta phenotype

(Jejina et al., 2024)

BicDR⁷¹, BicD^r, eEF1γ^A70 has macrochaeta phenotype

(Jejina et al., 2024)

BicDR⁷¹, eEF1γ^A70 has macrochaeta phenotype

(Jejina et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

eEF1γ^GE29510

(Fan et al., 2010)

Rescued by

eEF1γ^A70 is rescued by eEF1γ^UAS.cFa/Scer\GAL4^da.G32

(Fan et al., 2010)

Partially rescued by

eEF1γ^A70 is partially rescued by Scer\GAL4^da.G32/eEF1γ^S294A.UAS

(Fan et al., 2010)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

40963

w^*; eEF1γ^A70/TM6B, Tb¹

99884

w^*; P{UAS-eEF1γ.WT}1-4; eEF1γ^A70

99690

w^*; P{UAS-eEF1γ.S294A}25; eEF1γ^A70/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

EF192542

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

EF1γ^A70

(Jejina et al., 2024)

Ef1γ^A70

(Fan et al., 2010)

eEF1γ^A70

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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