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General Information
Symbol
Scer\GAL4Foma1
Species
S. cerevisiae
Name
FlyBase ID
FBal0241838
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GAL4}Foma1
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    Scer\GAL4Foma1 drives expression in a small cluster of optic lobe neurons that innervate the lobula complex and in the gamma lobe of the mushroom body. Five cells are labeled in the optic lobe, belonging to three distinc morphological types: one translobula plate neuron with processes in the lobula complex, one lobula columnar neuron which arborises in the proximal layers of the lobula and projects to the protocerebrum and three lobula plate tangential neurons with few processes in the lobula plate that project to the central brain.

    Scer\GAL4Foma1 labels a cluster of three neurons per optic lobe which extend arbours into layers of the lobula-plate.

     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 590 nm (red) light) of Scer\GAL4Foma1 neurons in adults significantly increases takeoff rates, compared to controls; these are a range of long and short duration takeoffs; a subset of these flies also display seizure-like leg extensions, seizures, but not takeoffs occur in decapitated flies due to activation.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Scer\GAL4Foma1
    Name Synonyms
    Failed optomotor assay-1
    Secondary FlyBase IDs
      References (3)