FlyBase Allele Report: Dmel\sktl[JF02796]

General Information

Symbol

Dmel\sktl^JF02796

Species

D. melanogaster

Name

FlyBase ID

FBal0242377

Feature type

allele

Associated gene

Dmel\sktl

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02796}

Also Known As

JF02796

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF02796}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02796

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by Rbf^HMS03004

(Parkhitko et al., 2021)

ameliorates cancer

modeled by Pten^HMS00044, Ras85D^G13Q.UAS, Rbf^HMS03004

(Parkhitko et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | adult stage, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

Phenotype Manifest In

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^Mef2.PR

(Neisch et al., 2025)

eye, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

ionotropic glutamate receptor complex | larval stage, with Scer\GAL4^Mef2.PR

(Neisch et al., 2025)

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in a necrotic eye phenotype.

(Pletcher et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

sktl^JF02796/Scer\GAL4^αTub84B.PL is a non-enhancer of increased cell number | P-stage | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

NOT Suppressor of

Statement

Reference

sktl^JF02796/Scer\GAL4^αTub84B.PL is a non-suppressor of increased cell number | P-stage | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

sktl^JF02796/Scer\GAL4^αTub84B.PL is a non-enhancer of interommatidial cell | P-stage | increased number | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

NOT Suppressor of

Statement

Reference

sktl^JF02796/Scer\GAL4^αTub84B.PL is a non-suppressor of interommatidial cell | increased number | P-stage | somatic clone - tissue specific phenotype of mtm^null

(Hu et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27715

y¹ v¹; P{TRiP.JF02796}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sktl^JF02796

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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