FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Uba1LL03617
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General Information
Symbol
Dmel\Uba1LL03617
Species
D. melanogaster
Name
FlyBase ID
FBal0243248
Feature type
allele
Associated gene
Dmel\Uba1
Associated Insertion(s)
PBac{SAstopDsRed}Uba1LL03617
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{SAstopDsRed}Uba1LL03617
    Cytology
    Description

    Insertion in the first intron.

    (Schuldiner et al., 2008)
    Allele components
    Component
    Use(s)
    Inserted element
    PBac{SAstopDsRed}
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Uba1LL03617 mutant clones in sensory neurons in adult wing do not display any defects in injury-induced axon degeneration (following an axotomy, the severed axons are cleared away normally).

        (Neukomm et al., 2017)

        Homozygous mushroom body neuroblast clones show neuroblast proliferation and axon pruning defects, and also show signs of axon degeneration.

        (Schuldiner et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Suppressor of
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The axon degeneration in sensory neurons clones in the adult wing expressing Ect4ΔARM.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4VGlut-OK371 can be suppressed by combination with Uba1LL03617.

        (Neukomm et al., 2017)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Uba1LL03617
        (Neukomm et al., 2017, Schuldiner et al., 2008)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)