FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Spc105Rwr1
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General Information
Symbol
Dmel\Spc105Rwr1
Species
D. melanogaster
Name
FlyBase ID
FBal0243498
Feature type
allele
Associated gene
Dmel\Spc105R
Associated Insertion(s)
Carried in Construct
P{gSpc105.wr1}
Key Links
Transgenic product class
inframe_deletion
(Schittenhelm et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Schittenhelm et al., 2009)
Mutagen
in vitro construct
(Schittenhelm et al., 2009)
Progenitor genotype
Carried in construct
P{gSpc105.wr1}
Cytology
Description

Contains Spc105R expressed under the control of its own genomic regulatory region, in which all but one of the repeats of the Spc105R middle linker region have been removed.

(Schittenhelm et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
Spc105R
Encoded product / tool
Spc105R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Spc105Rwr1 rescues Spc105R1

      (Schittenhelm et al., 2009)

      Spc105Rwr1 rescues Spc105RP01511LE

      (Schittenhelm et al., 2009)
      Partially rescues

      Spc105Rwr1 partially rescues Spc105RP01511LE/Spc105R1

      (Schittenhelm et al., 2009)
      Comments

      Spc105Rwr1 promotes the development of Spc105R1 and Spc105RP01511LE hemizygotes to fertile adults and almost completely rescues the abnormal anaphase/telophase figures seen during mitosis 16 in Spc105R1/Spc105RP01511LE embryos.

      (Schittenhelm et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Spc105Rwr1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)