FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ushVE25
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General Information
Symbol
Dmel\ushVE25
Species
D. melanogaster
Name
FlyBase ID
FBal0243668
Feature type
allele
Associated gene
Dmel\ush
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Biryukova and Heitzler, 2008)
Mutagen
ethyl methanesulfonate
(Biryukova and Heitzler, 2008)
Progenitor genotype
Cytology
Description

Nucleotide substitution from G to A into the GT donor site of splicing of 7th intron, resulting in a truncated (1046 aa) protein which lacks the 9th zinc finger domain.

(Biryukova and Heitzler, 2008)

Nucleotide substitution: G?A.

(Biryukova and Heitzler, 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:539,453..539,453 [+]
Nucleotide change:

G539453A

Comment:

G to A mutation in the splice donor site.

(Biryukova and Heitzler, 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In hemizygous conditions, ushVE25 mutants develop a mild cleft on the medium thorax.

      ushVE25/+ flies have the wildtype number of dorsocentral bristles.

      (Biryukova and Heitzler, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ushVE25/+; CtBPrev19/+ flies have the wildtype number of dorsocentral bristles.

      (Biryukova and Heitzler, 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ushVE25
      (Biryukova and Heitzler, 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)