FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\robo1::robo33.Ig2.1.Ig3.robo1.Tag:HA
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General Information
Symbol
Dmel\robo1::robo33.Ig2.1.Ig3.robo1.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0243832
Feature type
allele
Associated gene
robo1::robo3
Associated Insertion(s)
Carried in Construct
P{robo1-robo3Ig2::robo1Ig3-HA}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Spitzweck et al., 2010)
Progenitor genotype
Carried in construct
P{robo1-robo3Ig2::robo1Ig3-HA}
Cytology
Description

Contains 2386bp of the robo1 5' flanking region (coordinates 2R:18589619..18587234 , release 5 genome), which includes the region encoding the robo1 signal peptide up to residue Q52, 4 tandem Tag:HA tags, a fusion protein with the N-terminal part derived from robo3 (up to and including residue K210) and the C-terminal part derived from robo1 (starting from residue V251) and 2177bp of the robo1 3' flanking region (nucleotides 2R:18582049..18579873 , release 5 genome).

(Spitzweck et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
robo1
Encoded product / tool
robo1::robo3
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      robo::robo33.Ig2.1.Ig3.robo.T:Ivir\HA1 almost fully rescues the midline crossing errors seen in Fas2-expressing longitudinal axons of robo1 homozygous embryos.

      (Spitzweck et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      robo1::robo33.Ig2.1.Ig3.robo.T:Ivir\HA1
      robo1::robo33.Ig2.1.Ig3.robo1.T:Ivir\HA1
      robo1::robo33.Ig2.1.Ig3.robo1.Tag:HA
      robo::robo33.Ig2.1.Ig3.robo.T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)