FlyBase Allele Report: Dmel\pont[D302N.UAS]

General Information

Symbol

Dmel\pont^D302N.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0243875

Feature type

allele

Associated gene

Dmel\pont

Associated Insertion(s)

Carried in Construct

P{UAS-pont.D302N}

Key Links

Transgenic product class

missense_variant

(Diop et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Diop et al., 2008)

Mutagen

in vitro construct

(Diop et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-pont.D302N}

Cytology

Description

UAS regulatory sequences drive expression of of the pont product containing a point mutation (D302N) in the ATPase domain.

(Diop et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

pont

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^arm.PS

(Diop et al., 2008)

Phenotype Manifest In

wing, with Scer\GAL4^arm.PS

(Diop et al., 2008)

Detailed Description

Statement

Reference

The wings of adults expressing pont^{D302N.Scer\UAS} under the control of Scer\GAL4^arm.PS display a "held-out" phenotype in 5.3% of animals.

(Diop et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

pont^D302N.UAS/Scer\GAL4^arm.PS is an enhancer of visible | dominant phenotype of brm²

(Diop et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

pont^D302N.UAS/Scer\GAL4^arm.PS is an enhancer of wing phenotype of brm²

(Diop et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

The wings of brm²/+ animals expressing pont^{D302N.Scer\UAS} under the control of Scer\GAL4^arm.PS display a "held-out" phenotype in 35.5% of animals, much enhanced compared to brm²/+.

(Diop et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

pont^{D302N.Scer\UAS}

pont^D302N.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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