Less than 0.1% of homozygotes emerge as adult escapers (most homozygotes die as early pupae). The adult escapers have apparently normal morphology, except that their wings are opaque due to a failure of wing cells to undergo apoptosis.
Animals that are maternally and zygotically mutant for Nc are embryonic lethal, with almost complete absence of apoptosis.
γ-ray induced apoptosis (which is is seen in wild-type third larval instar wing discs after irradiation with 40Gy of γ-rays) is completely suppressed in NcΔA8 homozygotes.
In flies homozygous for NcΔA8, the pruning of ddaC dendrites is suppressed and many branches are still present 14-18 hours after puparium formation.