FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ube3a8O
Open Close
General Information
Symbol
Dmel\Ube3a8O
Species
D. melanogaster
Name
FlyBase ID
FBal0244595
Feature type
allele
Associated gene
Dmel\Ube3a
Associated Insertion(s)
Carried in Construct
Also Known As
dube3a8O
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Wu et al., 2008)
Progenitor genotype
P{EP}Ube3aEP3214
(Wu et al., 2008)
Caused by aberration
Df(3L)Ube3a8O
Cytology
Description

Deficiency breakpoint within Ube3a. Imprecise excision of the progenitor insertion resulting in a 2.4kb deletion which removes the transcription start site of Ube3a, and part of CG7600.

(Wu et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ube3a8O/+ flies have normal eyes.

      (Kim et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Ube3a8O/Ube3a[+] is a suppressor | partially of visible phenotype of Hsap\MECP2UAS.FL, Scer\GAL4GMR.PU

      (Kim et al., 2013)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ube3a8O/Ube3a[+] is a suppressor | partially of eye phenotype of Hsap\MECP2UAS.FL, Scer\GAL4GMR.PU

      (Kim et al., 2013)

      Ube3a8O/Ube3a[+] is a suppressor | partially of ommatidium phenotype of Hsap\MECP2UAS.FL, Scer\GAL4GMR.PU

      (Kim et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Ube3a8O/+ suppresses rough eye phenotypes with ommatidial disorganization in flies with expression of Hsap\MECP2Scer\UAS.FL driven by Scer\GAL4GMR.PU.

      (Kim et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      80
      (Kim et al., 2013)
      Dube3a8O
      (Ferdousy et al., 2011)
      Ube3a8O
      dube3a8O
      (Wu et al., 2008, Wu et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)