FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kibra4
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General Information
Symbol
Dmel\kibra4
Species
D. melanogaster
Name
FlyBase ID
FBal0244822
Feature type
allele
Associated gene
Dmel\kibra
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Baumgartner et al., 2010)
Mutagen
recombination
(Baumgartner et al., 2010)
Progenitor genotype
P{EP}kibraEP666
(Baumgartner et al., 2010)
P{EPgy2}MeltrinEY00279
(Baumgartner et al., 2010)
Cytology
Description

Generated by recombination between the two progenitor insertions.

(Baumgartner et al., 2010)

The entire kibra locus has been removed.

(Baumgartner et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:14,697,316..14,723,812 [-]
Comment:

Generated by P-element induced recombination between P{EP}kibraEP666 and P{EPgy2}MeltrinEY00279.

(Baumgartner et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      kibra4 eye clones show an increase in the ratio of pale vs yellow photoreceptor cells R8.

      (Pojer et al., 2021)

      Eyes homozygous for kibra4 (generated by the eyFLP method) are enlarged compared to controls.

      Homozygous clones in the pupal retina have an increase in the number of interommatidial cells.

      (Baumgartner et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of AckScer\UAS.T:SV5\V5 under the control of Scer\GAL4Ubi.PU in the kibra4 homozygous somatic clones (induced using the eyFLP method) promotes tissue overgrowth in the adult eye.

      (Hu et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      kibra4 is rescued by kibraUAS.cBa

      (Baumgartner et al., 2010)
      Comments

      kibraScer\UAS.cBa rescues the lethality of kibra4 homozygotes in the absence of a Scer\GAL4 driver.

      (Baumgartner et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Kibra4
      (Baumgartner et al., 2010, Baumgartner et al., 2010)
      kibra4
      (Pojer et al., 2021, Gusareva et al., 2018, Hu et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)