FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tsc1JF01484
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General Information
Symbol
Dmel\Tsc1JF01484
Species
D. melanogaster
Name
FlyBase ID
FBal0245748
Feature type
allele
Associated gene
Dmel\Tsc1
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01484}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
in vitro construct
(Ni et al., 2008)
Progenitor genotype
Carried in construct
P{TRiP.JF01484}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01484
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression under the control of Scer\GAL4eya.enh1+E+2 results in large and rough eye phenotype.

      (Pletcher et al., 2019)

      Expression of Tsc1JF01484 in cardiac muscle under the control of Scer\GAL4GMR88D05 has no effect on pupal eclosion rates.

      Expression of Tsc1JF01484 in skeletal muscle under the control of Scer\GAL4how-24B has no effect on pupal eclosion rates.

      (Hatfield et al., 2015)

      Expression of Tsc1JF01484 under the control of Scer\GAL4Mef2.PR is able to significantly suppress the formation of autophagosomes in the muscles of chloroquine-treated larvae starved on low-nutrient food for 6 hours.

      (Zirin et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The small underdeveloped wing characteristic for adult flies expressing MitfScer\UAS.cZa under the control of Scer\GAL4dpp.blk1 is significantly suppressed by co-expression of Tsc1JF01484.

      (Zhang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tsc1JF01484
      Tsc1Ri
      (Gupta and Stocker, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)