FlyBase Allele Report: Dmel\Mitf[UAS.cZa]

General Information

Symbol

Dmel\Mitf^UAS.cZa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Zhang

FlyBase ID

FBal0324137

Feature type

allele

Associated gene

Dmel\Mitf

Associated Insertion(s)

Carried in Construct

P{UAS-Mitf.Z}

Also Known As

UAS-Mitf

Key Links

Transgenic product class

wild_type

(Zhang et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Zhang et al., 2015)

Mutagen

in vitro construct

(Zhang et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Mitf.Z}

Cytology

Description

UAS regulatory sequences drive expression of wild-type Mitf.

(Zhang et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mitf

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage | somatic clone - tissue specific, with Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

visible | adult stage, with Scer\GAL4^dpp.blk1

(Zhang et al., 2024, Zhang et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Mitf^Scer\UAS.cZa under the control of Scer\GAL4^dpp.blk1 results in very small under-developed wings in adult flies and morphological third instar wing disc defects (with the Scer\GAL4[nub.PK] driver) as well as expansion of acidic compartments in the wing discs (with the Scer\GAL4^en-e16E driver).

(Zhang et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Suppressed by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, suppressible by Cka⁰⁵⁸³⁶/Cka[+]

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible by Cka⁰⁵⁸³⁶/Cka[+]

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by mts[+]/mts⁰²⁴⁹⁶

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible by Vha13[+]/Vha13^CA07644

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by Vha26^CC01380/Vha26[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible by Vha55[+]/Vha55¹⁶

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by Vha68-2[+]/Vha68-2^R6

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by VhaSFD^G00259/VhaSFD[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by Rab2^CA07465/Rab2[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by CtsL1^CC01377/Cp1[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by spin[+]/spin^Delta58

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by Lamp1^HMS01698, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by gig^HM04083, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by gig[+]/gig¹⁰⁹

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by Tsc1^JF01484, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, suppressible | partially by RagC-D^EY11726, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

NOT suppressed by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by ey^UAS.cHa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by eya^UAS.cBa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has visible | adult stage phenotype, non-suppressible by Vha16-1^unspecified

(Zhang et al., 2015)

NOT Enhancer of

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

NOT Suppressor of

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-enhanceable by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-enhanceable by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-enhanceable by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Suppressed by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, suppressible by Cka⁰⁵⁸³⁶/Cka[+]

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, suppressible by Cka⁰⁵⁸³⁶/Cka[+]

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing phenotype, suppressible by Cka⁰⁵⁸³⁶/Cka[+]

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing phenotype, suppressible | partially by mts[+]/mts⁰²⁴⁹⁶

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible by Vha14-1[+]/Vha14-1^EY12998

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible by Vha13[+]/Vha13^CA07644

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Vha26^CC01380/Vha26[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible by Vha55[+]/Vha55¹⁶

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Vha68-2[+]/Vha68-2^R6

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by VhaSFD^G00259/VhaSFD[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Rab2^CA07465/Rab2[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by CtsL1^CC01377/Cp1[+]

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by spin[+]/spin^Delta58

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Lamp1^HMS01698, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by gig^HM04083, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by gig[+]/gig¹⁰⁹

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Tsc1^JF01484, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, suppressible | partially by RagC-D^EY11726, Scer\GAL4^dpp.blk1

(Zhang et al., 2015)

NOT suppressed by

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by ey^UAS.cHa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by eya^UAS.cBa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-suppressible by yki^{UAS.EGFP,Tag:HA}, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-suppressible by yki[+]/yki^B5

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI has developing neuron | larval stage | decreased number | somatic clone - tissue specific phenotype, non-suppressible by yki^HMS00041, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^dpp.blk1 has wing | adult stage phenotype, non-suppressible by Vha16-1^unspecified

(Zhang et al., 2015)

NOT Enhancer of

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of eye disc | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of developing neuron | larval stage | ectopic | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of developing neuron | larval stage | ectopic | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of eye disc | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-enhancer of peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

NOT Suppressor of

Statement

Reference

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of developing neuron | ectopic | larval stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PI, Strip^HMS01134

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of developing neuron | ectopic | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Mitf^UAS.cZa, Scer\GAL4^Act5C.PI is a non-suppressor of peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype of Cka^HMS00081, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

The small underdeveloped wing characteristic for adult flies expressing Mitf^Scer\UAS.cZa under the control of Scer\GAL4^dpp.blk1 is significantly suppressed by combination with a single copy of any of the following: Vha14-1^EY12998, Vha13^CA07644, Vha26^CC01380, Vha55¹⁶, Vha68-2^R6, VhaSFD^G00259, Rab2^CA07465, Cp1^CC01377, spin^Delta58 and gig¹⁰⁹ or by co-expression of Lamp1^HMS01698, gig^HM04083, Tsc1^JF01484 or RagC-D^EY11726 but is not affected by combination with Vha16-1^unspecified.

(Zhang et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mitf^Scer\UAS.cZa

Mitf^UAS.cZa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Zhang

Secondary FlyBase IDs

References (4)

Report Sections

Open Close