FlyBase Allele Report: Dmel\Strip[HMS01134]

General Information

Symbol

Dmel\Strip^HMS01134

Species

D. melanogaster

Name

FlyBase ID

FBal0257795

Feature type

allele

Associated gene

Dmel\Strip

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01134}

Also Known As

UAS-strip^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01134}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01134

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

autophagosome | increased number | larval stage, with Scer\GAL4^Mef2.PR

(Guo et al., 2023)

developing neuron | ectopic | larval stage | somatic clone - tissue specific, with Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

embryonic/larval hypodermal muscle | larval stage, with Scer\GAL4^Mef2.PR

(Guo et al., 2023)

eye disc | larval stage | somatic clone - tissue specific, with Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

indirect flight muscle cell | pupal stage, with Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

investment cone, with Scer\GAL4^{VP16.nanos.UTR}

(Santos et al., 2023)

myotube | pupal stage, with Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific, with Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

sarcomere | larval stage, with Scer\GAL4^Mef2.PR

(Guo et al., 2023)

seminal vesicle, with Scer\GAL4^{VP16.nanos.UTR}

(Santos et al., 2023)

spermatozoon | absent, with Scer\GAL4^{VP16.nanos.UTR}

(Santos et al., 2023)

terminal epithelium of testis, with Scer\GAL4^{VP16.nanos.UTR}

(Santos et al., 2023)

ventral longitudinal muscle 3 | larval stage, with Scer\GAL4^Mef2.PR

(Guo et al., 2023)

ventral longitudinal muscle 4 | larval stage, with Scer\GAL4^Mef2.PR

(Guo et al., 2023)

Detailed Description

Statement

Reference

The expression of Strip^HMS01134 under the control of Scer\GAL4^Mef2.PR leads to indirect flight muscle atrophy during pupal development (after 32h APF); fibers are longer than in controls and fail to compact at 32h APF.

(Kaya-Çopur et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^Mef2.PR, Strip^HMS01134 has increased body size | P-stage phenotype, enhanceable by stv¹

(Guo et al., 2023)

Scer\GAL4^Mef2.PR, Strip^HMS01134 has increased body size | P-stage phenotype, enhanceable by Nuak^K99R

(Guo et al., 2023)

NOT Enhanced by

Statement

Reference

Scer\GAL4^Act5C.PI, Strip^HMS01134 has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^Act5C.PI, Strip^HMS01134 has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, non-suppressible by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Suppressor of

Statement

Reference

Strip^HMS01134, Scer\GAL4^Myo31DF.PU is a suppressor of increased occurrence of cell division | adult stage phenotype of PXo^HMS01023, Scer\GAL4^Myo31DF.PU

(Xu et al., 2023)

Strip^HMS01134, Scer\GAL4^esg.PU is a suppressor of increased occurrence of cell division | adult stage phenotype of PXo^HMS01023, Scer\GAL4^esg.PU

(Xu et al., 2023)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^Mef2.PR, Strip^HMS01134 has embryonic/larval hypodermal muscle | larval stage phenotype, enhanceable by stv¹

(Guo et al., 2023)

Scer\GAL4^Mef2.PR, Strip^HMS01134 has embryonic/larval hypodermal muscle | larval stage phenotype, enhanceable by Nuak^K99R

(Guo et al., 2023)

NOT Enhanced by

Statement

Reference

Scer\GAL4^Act5C.PI, Strip^HMS01134 has eye disc | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Scer\GAL4^Act5C.PI, Strip^HMS01134 has peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype, non-enhanceable by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Scer\GAL4^Act5C.PI, Strip^HMS01134 has developing neuron | larval stage | ectopic | somatic clone - tissue specific phenotype, non-enhanceable by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^Act5C.PI, Strip^HMS01134 has eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Scer\GAL4^Act5C.PI, Strip^HMS01134 has peripodial epithelium of eye disc | larval stage | somatic clone - tissue specific phenotype, non-suppressible by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Scer\GAL4^Act5C.PI, Strip^HMS01134 has developing neuron | ectopic | larval stage | somatic clone - tissue specific phenotype, non-suppressible by Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

Suppressor of

Statement

Reference

Strip^HMS01134, Scer\GAL4^Myo31DF.PU is a suppressor of adult midgut phenotype of PXo^HMS01023, Scer\GAL4^Myo31DF.PU

(Xu et al., 2023)

Strip^HMS01134, Scer\GAL4^esg.PU is a suppressor of adult midgut phenotype of PXo^HMS01023, Scer\GAL4^esg.PU

(Xu et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

34657

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01134}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG11526^HMS01134

Strip^HMS01134

(Neisch et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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