FlyBase Allele Report: Dmel\ey[UAS.cHa]

(Wang and Sun, 2012, Benassayag et al., 2003, Jang et al., 2003, Bessa et al., 2002, Plaza et al., 2001, Bui et al., 2000, Curtiss and Mlodzik, 2000, Seimiya and Gehring, 2000, Bonini et al., 1997)

eye | ectopic, with Scer\GAL4^MS941

(Halder et al., 1995)

eye | ectopic, with Scer\GAL4^upd1-E132

(Seimiya and Gehring, 2000, Halder et al., 1995)

eye | ectopic | somatic clone, with Scer\GAL4^30A

(Kango-Singh et al., 2003)

eye | ectopic | somatic clone, with Scer\GAL4^Act5C.PI

(Kango-Singh et al., 2003)

eye | ectopic | somatic clone, with Scer\GAL4^ap-md544

(Kango-Singh et al., 2003)

eye | ectopic | somatic clone, with Scer\GAL4^bi-omb-Gal4

(Kango-Singh et al., 2003)

eye photoreceptor cell & dorsal mesothoracic disc | ectopic, with Scer\GAL4^dpp.blk1

(Anderson et al., 2006)

eye photoreceptor cell & ventral thoracic disc | ectopic, with Scer\GAL4^dpp.blk1

(Anderson et al., 2006)

eye photoreceptor cell | ectopic & antennal disc, with Scer\GAL4^dpp.blk1

(Anderson et al., 2006)

glial cell, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

haltere, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

haltere & eye | ectopic, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

haltere & ommatidium | ectopic, with Scer\GAL4^dpp.blk1

(Bonini et al., 1997)

haltere | proximal, with Scer\GAL4^dpp.blk1

(Jang et al., 2003)

haltere disc, with Scer\GAL4^30A

(Chen et al., 1999)

Kenyon cell, with Scer\GAL4^238Y

(Noveen et al., 2000)

larval intersegmental nerve, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

larval longitudinal connective, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

larval segmental nerve, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

larval ventral nerve cord, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

lateral cervical tract, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

leg, with Scer\GAL4^dpp.blk1

(Jang et al., 2003, Halder et al., 1998, Bonini et al., 1997)

leg, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

leg & eye | ectopic, with Scer\GAL4^dpp.blk1

(Halder et al., 1998)

leg & eye | ectopic, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

leg disc, with Scer\GAL4^hs.2sev

(Niwa et al., 2004)

mushroom body vertical lobe, with Scer\GAL4^238Y

(Noveen et al., 2000)

mushroom body vertical lobe, with Scer\GAL4^hs.PB

(Noveen et al., 2000)

neuron | ectopic, with Scer\GAL4^30A

(Chen et al., 1999)

ommatidium, with Scer\GAL4^ey.PH

(Curtiss and Mlodzik, 2000)

ommatidium, with Scer\GAL4^lz-gal4

(Atkins et al., 2013)

ommatidium | ectopic, with Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

ommatidium | ectopic, with Scer\GAL4^dpp.blk1

(Bonini et al., 1997)

photoreceptor | ectopic | somatic clone, with Scer\GAL4^Act5C.PI

(Kango-Singh et al., 2003)

photoreceptor | ectopic | third instar larval stage, with Scer\GAL4^dpp.blk1

(Wang and Sun, 2012)

proboscis & ommatidium | ectopic, with Scer\GAL4^dpp.blk1

(Bonini et al., 1997)

retina | ectopic, with Scer\GAL4^30A

(Chen et al., 1999)

rhabdomere, with Scer\GAL4^lz-gal4

(Atkins et al., 2013)

symmetrical commissure, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

tibia, with Scer\GAL4^Act5C.PI

(Niwa et al., 2004)

tritocerebral commissure, with Scer\GAL4^sca-537.4

(Kammermeier et al., 2001)

ventral thoracic disc & eye | ectopic, with Scer\GAL4^dpp.blk1

(Bonini et al., 1997)

vertical lobe of adult mushroom body, with Scer\GAL4^238Y

(Noveen et al., 2000)

vertical lobe of adult mushroom body, with Scer\GAL4^ey-OK107

(Furukubo-Tokunaga et al., 2009)

vertical lobe of adult mushroom body, with Scer\GAL4^hs.PB

(Noveen et al., 2000)

wing, with Scer\GAL4^30A

(Chen et al., 1999)

wing, with Scer\GAL4^Act5C.PI

(Niwa et al., 2004)

wing, with Scer\GAL4^Bx-MS1096

(Yoshioka et al., 2007)

wing, with Scer\GAL4^dpp.blk1

(Bessa et al., 2002, Bonini et al., 1997)

wing, with Scer\GAL4^MS941

(Halder et al., 1995)

wing, with Scer\GAL4^p339

(Halder et al., 1995)

wing, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

wing & eye | ectopic, with Scer\GAL4^MS941

(Halder et al., 1995)

wing & eye | ectopic, with Scer\GAL4^upd1-E132

(Halder et al., 1995)

wing | proximal, with Scer\GAL4^dpp.blk1

(Jang et al., 2003)

wing disc, with Scer\GAL4^30A

(Chen et al., 1999)

wing disc, with Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

wing disc, with Scer\GAL4^hs.2sev

(Niwa et al., 2004)

wing disc | posterior | somatic clone, with Scer\GAL4^30A

(Kango-Singh et al., 2003)

wing disc | posterior | somatic clone, with Scer\GAL4^Act5C.PI

(Kango-Singh et al., 2003)

wing disc | posterior | somatic clone, with Scer\GAL4^ap-md544

(Kango-Singh et al., 2003)

wing disc | posterior | somatic clone, with Scer\GAL4^bi-omb-Gal4

(Kango-Singh et al., 2003)

wing disc | somatic clone | third instar larval stage, with Scer\GAL4^Act5C.PI

(Tanaka-Matakatsu et al., 2015)

wing disc | third instar larval stage, with Scer\GAL4^Bx-MS1096

(Bunker et al., 2015)

wing hinge, with Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2015, Tanaka-Matakatsu et al., 2014)

wing hinge, with Scer\GAL4^Bx-MS1096

(Bessa and Casares, 2005)

wing hinge, with Scer\GAL4^dpp.blk1

(Bessa et al., 2002)

Detailed Description

Statement

Reference

Expression of ey^UAS.cHa under the control of Scer\GAL4^elav-C155 does not increase mitotic proliferation in the ventral nerve cord during late embryogenesis, compared to controls.

(Curt et al., 2019)

The expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^Bx-MS1096 induces ectopic photoreceptor formation in a small proportion of third instar larval wing disc cells, as compared to controls.

(Bunker et al., 2015)

While Scer\GAL4^Act5C.PI>ey^Scer\UAS.cHa expressing clones are significantly larger than wild-type controls located in the notum region of the wing disc, no significant difference is observed for clones located in the pouch or hinge region.

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^30A induces ectopic eye on the wing hinge.

Co-expression of ey^{ΔPD.cWa.Scer\UAS} significantly decreases the ability of Scer\GAL4^30A>ey^Scer\UAS.cHa to induce ectopic eye formation.

Co-expression of ey^Scer\UAS.cTa significantly decreases the ability of Scer\GAL4^30A>ey^Scer\UAS.cHa to induce ectopic eye formation.

(Tanaka-Matakatsu et al., 2015)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^30A induces ectopic eye formation on the wing hinge.

(Tanaka-Matakatsu et al., 2014)

Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^lz-gal4 show defects in ommatidial shape and pigment. Rhabdomere morphogenesis and ommatidial rotation are abnormal.

(Atkins et al., 2013)

A small cluster of differentiating ectopic ommatidia (occupying approximately 15% of the disc surface area) are formed in the wing disc in animals expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^ap-md544.

(Nfonsam et al., 2012)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 results in ectopic eyes in the wing, antenna and leg. Photoreceptors formation is induced in the third instar larval wing disc.

(Wang and Sun, 2012)

Expression of ey^UAS.cHa under the control of Scer\GAL4^ey.PU leads to small and rough eyes when compared to controls.

(Hoang et al., 2010)

Overexpression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey-OK107 results in larval lethality. The larval mushroom bodies of these animals exhibit marked abnormalities, with 73% exhibiting either degeneration or absence of the dorsal lobes.

(Furukubo-Tokunaga et al., 2009)

Expression of ey^Scer\UAS.cHa via Scer\GAL4^cb41, Scer\GAL4^cb49 or Scer\GAL4^sd.PU fails to induce ectopic eyes.

(Weasner et al., 2007)

Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^Bx-MS1096 have ectopic eye structures in the wing.

(Yoshioka et al., 2007)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 in the antennal, wing or leg disc, causes a subset of cells to be transformed into photoreceptors.

(Anderson et al., 2006)

Expression of ey^Scer\UAS.cHa driven by Scer\GAL4^Bx-MS1096, induces ectopic eyes on the wing hinge, but not on the head.

(Bessa and Casares, 2005)

ey^Scer\UAS.cHa, expressed under the control of Scer\GAL4^hs.2sev, generates ectopic "eyes" (using Ecol\lacZ^{GMR.T:SV40\nls2} as a marker to visualize eye differentiation) in leg and wing discs, but only when expressed at ~80h after egg laying (AEL), which is the time of endogenous sensory organ development. These ectopic "eyes" are formed only in small groups of cells located close to the anterior-posterior compartment boundary. Ectopic expression of ey^Scer\UAS.cHa, driven by Scer\GAL4^Act5C.PI, produces ectopic eyes in the wing blade and leg tibial segment; these eyes are surrounded by long sensory bristles that resemble the hairs that surround the endogenous eye.

(Niwa et al., 2004)

When ey^Scer\UAS.cHa is driven by Scer\GAL4^dpp.blk1 an ectopic eye phenotype is seen.

(Benassayag et al., 2003)

When ey^Scer\UAS.cHa is driven by Scer\GAL4^dpp.blk1, ectopic eyes are seen. These are seen at the base of antennae, wings and halteres and on leg segments. No extra photoreceptors are detected at the ventral margin in the eye-antennal disc.

(Jang et al., 2003)

When clones expressing ey^Scer\UAS.cHa (driven by Scer\GAL4^Act5C.PI) are made in the eye disc, no effect on growth or photoreceptor differentiation is seen when posterior to the morphogenetic furrow (MF), no affected growth or induced ectopic eyes when anterior to the MF, except that ectopic photoreceptors are induced in 6% of the clones in the ocellar region. In wing discs clones are associated with overgrowths, whereas eye induction is observed in about a third of clones that are located within the posterior compartment or along the anterior-posterior compartmental boundary. the induction of eye is not dependant on the size of the clone. No clones in the Anterior compartment show ectopic eye induction, even if the clone is quite large. When clones expressing ey^Scer\UAS.cHa (driven by Scer\GAL4^bi-omb-Gal4, Scer\GAL4^30A or Scer\GAL4^ap-md544) in the wing disc, ectopic eyes are only seen when clones are made at the A/P border or in the posterior compartment. This is true whether clones are induced in the first, second and early third larval instar stages, though frequency of eye induction is highest when induced in the first instar.

(Kango-Singh et al., 2003)

Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 show a transformation of wing hinge to eye. Wing blade development is partially suppressed.

(Bessa et al., 2002)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey.PH results in flies with reduced eyes. Most of the flies eclose.

(Jiao et al., 2001)

When ey^Scer\UAS.cHa is driven by Scer\GAL4^sca-537.4, strong defects in the formation of the embryonic CNS are seen. In the ventral nerve cord of these embryos, the longitudinal axon pathways are severely disrupted, the anterior and posterior commissures are fused, the segmental and intersegmental nerves are perturbed and the spatial pattern of the majority of the glial cells is deranged. The midline glial cells are positioned correctly. Sever axonal defects are also seen in the developing brain. The tritocerebral commissure is missing in almost all embryos and the major preoral brain commissure is absent approximately half the time. Furthermore, the longitudinal pathways of the embryonic brain, including the embryonic circumesophageal connectives are strongly reduced or absent, and the frontal connectives are absent or misrouted. However no gross perturbations in the overall formation of the neuromeres are seen in the embryonic brain.

(Kammermeier et al., 2001)

Expression of ey^Scer\UAS.cHa driven by Scer\GAL4^dpp.blk1 causes ectopic retinal development, leading to the eventual formation of ectopic compound eyes in the adult.

(Bui et al., 2000)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey.PH results in flies with smaller eyes than normal (which contain fewer facets than wild-type eyes). The regular arrangement of facets is lost in these eyes. Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 results in the induction of ectopic eyes.

(Curtiss and Mlodzik, 2000)

When expression is driven by Scer\GAL4^238Y, 72% of larvae show unilateral or bilateral reduction or absence of dorsal lobes. A smaller fraction had fusion of medial lobes. The number of Kenyon cells is reduced. The diameter of the MB peduncle is not reduced. When expression is driven by Scer\GAL4^hs.PB at early stages of embryogenesis the embryos do not survive. But overexpression at stage 16 causes similar dorsal lobe defects to those seen with Scer\GAL4^238Y.

(Noveen et al., 2000)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^E132 results in the formation of ectopic eyes. Ectopic eyes are produced at a frequency of 100% if ey^Scer\UAS.cHa is expressed under the control of Scer\GAL4^dpp.blk1.

(Seimiya and Gehring, 2000)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^30A results in the induction of neurons at the anterior/posterior boundary of the wing disc and dorsal to the wing pouch. Ectopic neurons are also induced on the ventral side of the haltere disc. Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^30A do not develop ectopic eyes on the haltere and only small patches of retinal tissue appear on the ventral side of the wing hinge at 20% penetrance.

(Chen et al., 1999)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^unspecified produces a disrupted eye phenotype.

(Warrick et al., 1999)

When expression is driven by Scer\GAL4^dpp.blk1, extra eye structures appear on otherwise deformed leg.

(Halder et al., 1998)

Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 in a wild-type background develop ectopic eyes on the antennal portion of the eye-antennal discs and on the leg and wing discs. Ommatidial development is also sometimes seen on the haltere and proboscis.

(Bonini et al., 1997)

Scer\GAL4^dpp.blk1 mediated expression in dac¹ or dac³ mutant background is unable to induce ectopic eye formation.

(Shen and Mardon, 1997)

When expressed via Scer\GAL4^E132, ectopic eyes are induced in the wing, leg, antenna and haltere. At 25^oC 100% of flies produce ectopic eye structures. In some cases the ectopic eyes cause pattern duplications in the surrounding tissues. When expressed via Scer\GAL4^MS941, all flies produce eye facets on both wings. When expressed via Scer\GAL4^p339, red pigment spots are formed, with 100% penetrance. Ectopic eyes most frequently occur on structures derived from the antennal and wing discs. Distinct ommatidia have lenses and interommatidial bristles. The array of facets and bristles is largely normal. The eye structures on the legs are on average smaller than those on antennae or wings but have relatively normal organization. Ectopic eyes have normal photoreceptor cells (with rhabdomeres), cornea, cone cells and primary, secondary and tertiary pigment cells. The sequence of neuronal differentiation of the normal eye is retained in the ectopic eye cells. Morphogenesis of the ectopic eyes is normal and probably involves the formation of an ectopic morphogenetic furrow.

(Halder et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^30A, ey^UAS.cHa has visible phenotype, enhanceable by da^UAS.cGa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has visible phenotype, enhanceable by da^{da-da.cTa.UAS}/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has visible phenotype, enhanceable by Scer\GAL4^30A/dac^UAS.cSa

(Chen et al., 1999)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has visible phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Suppressed by

Statement

Reference

Scer\GAL4^30A, ey^UAS.cHa has visible phenotype, suppressible | partially by ato::da^UAS.cTa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has visible | adult stage phenotype, suppressible by Scer\GAL4^dpp.blk1/ct^UAS.cPa

(Wang and Sun, 2012)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has visible | adult stage phenotype, suppressible by hth^UAS.cPa/Scer\GAL4^dpp.blk1

(Wang and Sun, 2012)

Scer\GAL4^ey.PU, ey^UAS.cHa has abnormal size | adult stage phenotype, suppressible | partially by CtBP[+]/CtBP^87De-10

(Hoang et al., 2010)

Scer\GAL4^ey.PU, ey^UAS.cHa has visible | adult stage phenotype, suppressible | partially by CtBP[+]/CtBP^87De-10

(Hoang et al., 2010)

Scer\GAL4^Bx-MS1096, ey^UAS.cHa has visible phenotype, suppressible | partially by Nf-YA^UAS.Tag:HA, Scer\GAL4^Bx-MS1096

(Yoshioka et al., 2007)

NOT suppressed by

Statement

Reference

Scer\GAL4^unspecified, ey^UAS.cHa has visible phenotype, non-suppressible by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^unspecified

(Warrick et al., 1999)

Enhancer of

Statement

Reference

ey^UAS.cHa, Scer\GAL4^ey.PH is an enhancer of visible phenotype of H^UAS.cGa, Scer\GAL4^ey.PH

(Lee et al., 2009)

ey^UAS.cHa/Scer\GAL4^ey.PH is an enhancer of visible | recessive phenotype of dpp^d-blk

(Curtiss and Mlodzik, 2000)

Suppressor of

Statement

Reference

Scer\GAL4^toy1/ey^UAS.cHa is a suppressor | partially of lethal | pharate adult stage phenotype of toy^hdl

(Jacobsson et al., 2009)

Scer\GAL4^toy1/ey^UAS.cHa is a suppressor | partially of partially lethal - majority die | pharate adult stage phenotype of toy^G7.39

(Jacobsson et al., 2009)

ey^UAS.cHa, Scer\GAL4^ey-OK107 is a suppressor of visible phenotype of Antp^UAS.cBa, Scer\GAL4^ey-OK107

(Plaza et al., 2008)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Scer\GAL4^ey.PH, gsb^UAS.cJa

(Jiao et al., 2001)

NOT Suppressor of

Statement

Reference

ey^UAS.cHa, Scer\GAL4^Act5C.PI is a non-suppressor of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

ey^UAS.cHa/Scer\GAL4^Bx-MS1096 is a non-suppressor of neoplasia | third instar larval stage phenotype of Scer\GAL4^Bx-MS1096, dlg1^HMS01954

(Bunker et al., 2015)

Other

Statement

Reference

Scer\GAL4^bi-omb-Gal4, dpp^UAS.cSa, ey^UAS.cHa, hh^UAS.cAa has lethal | larval stage phenotype

(Kango-Singh et al., 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^30A, ey^UAS.cHa has wing hinge phenotype, enhanceable by da^UAS.cGa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has eye | ectopic phenotype, enhanceable by da^UAS.cGa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has wing hinge phenotype, enhanceable by da^{da-da.cTa.UAS}/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has eye | ectopic phenotype, enhanceable by da^{da-da.cTa.UAS}/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^ap-md544, ey^UAS.cHa has wing disc phenotype, enhanceable by dpp^UAS.cSa/Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

Scer\GAL4^ap-md544, ey^UAS.cHa has ommatidium | ectopic phenotype, enhanceable by dpp^UAS.cSa/Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

Scer\GAL4^ap-md544, ey^UAS.cHa has wing disc phenotype, enhanceable by Scer\GAL4^ap-md544/hh^UAS.cCa

(Nfonsam et al., 2012)

Scer\GAL4^ap-md544, ey^UAS.cHa has ommatidium | ectopic phenotype, enhanceable by Scer\GAL4^ap-md544/hh^UAS.cCa

(Nfonsam et al., 2012)

Scer\GAL4^ap-md544, ey^UAS.cHa has wing disc phenotype, enhanceable by N^ICN.UAS, Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

Scer\GAL4^ap-md544, ey^UAS.cHa has ommatidium | ectopic phenotype, enhanceable by N^ICN.UAS, Scer\GAL4^ap-md544

(Nfonsam et al., 2012)

Scer\GAL4^hs.2sev, ey^UAS.cHa has leg disc phenotype, enhanceable by tkv^CA.UAS.cUa

(Niwa et al., 2004)

Scer\GAL4^hs.2sev, ey^UAS.cHa has wing disc phenotype, enhanceable by tkv^CA.UAS.cUa

(Niwa et al., 2004)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye disc phenotype, enhanceable by Scer\GAL4^dpp.blk1/eyg^UAS.lune

(Jang et al., 2003)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, enhanceable by Scer\GAL4^dpp.blk1/eyg^UAS.lune

(Jang et al., 2003)

Scer\GAL4^Act5C.PI, ey^UAS.cHa, hh^UAS.cAa has wing disc | somatic clone phenotype, enhanceable by dpp^UAS.cSa/Scer\GAL4^Act5C.PI

(Kango-Singh et al., 2003)

Scer\GAL4^bi-omb-Gal4, ey^UAS.cHa has eye | ectopic phenotype, enhanceable by ci^UAS.Tag:HA/Scer\GAL4^bi-omb-Gal4

(Kango-Singh et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, eya^UAS.cPa has wing disc phenotype, enhanceable by so^UAS.cPa/Scer\GAL4^30A

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, eya^UAS.cPa has photoreceptor neuron | ectopic phenotype, enhanceable by so^UAS.cPa/Scer\GAL4^30A

(Pappu et al., 2003)

Scer\GAL4^30A, ey^UAS.cHa has wing disc phenotype, enhanceable by Scer\GAL4^30A/dac^UAS.cSa

(Chen et al., 1999)

Scer\GAL4^30A, ey^UAS.cHa has wing phenotype, enhanceable by Scer\GAL4^30A/dac^UAS.cSa

(Chen et al., 1999)

Scer\GAL4^30A, ey^UAS.cHa has haltere phenotype, enhanceable by Scer\GAL4^30A/dac^UAS.cSa

(Chen et al., 1999)

Scer\GAL4^30A, ey^UAS.cHa has wing disc phenotype, enhanceable by dpp^UAS.cSa/Scer\GAL4^30A

(Chen et al., 1999)

Scer\GAL4^30A, ey^UAS.cHa has wing disc phenotype, enhanceable by eya^UAS.cPa/Scer\GAL4^30A

(Chen et al., 1999)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has proboscis phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has haltere phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has leg phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has wing phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has antenna phenotype, enhanceable by Scer\GAL4^dpp.blk1/eya^UAS.cBa

(Bonini et al., 1997)

Suppressed by

Statement

Reference

Scer\GAL4^30A, ey^UAS.cHa has wing hinge phenotype, suppressible | partially by ato::da^UAS.cTa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^30A, ey^UAS.cHa has eye | ectopic phenotype, suppressible | partially by ato::da^UAS.cTa/Scer\GAL4^30A

(Tanaka-Matakatsu et al., 2014)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, suppressible by Scer\GAL4^dpp.blk1/ct^UAS.cPa

(Wang and Sun, 2012)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, suppressible by hth^UAS.cPa/Scer\GAL4^dpp.blk1

(Wang and Sun, 2012)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has photoreceptor | ectopic | third instar larval stage phenotype, suppressible by Scer\GAL4^dpp.blk1/ct^UAS.cPa

(Wang and Sun, 2012)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has photoreceptor | ectopic | third instar larval stage phenotype, suppressible by hth^UAS.cPa/Scer\GAL4^dpp.blk1

(Wang and Sun, 2012)

Scer\GAL4^ey.PU, ey^UAS.cHa has eye phenotype, suppressible | partially by CtBP[+]/CtBP^87De-10

(Hoang et al., 2010)

Scer\GAL4^Bx-MS1096, ey^UAS.cHa has wing phenotype, suppressible | partially by Nf-YA^UAS.Tag:HA, Scer\GAL4^Bx-MS1096

(Yoshioka et al., 2007)

Scer\GAL4^Bx-MS1096, ey^UAS.cHa has eye | ectopic phenotype, suppressible | partially by Nf-YA^UAS.Tag:HA, Scer\GAL4^Bx-MS1096

(Yoshioka et al., 2007)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has wing disc phenotype, suppressible by wg^UAS.cLa/Scer\GAL4^dpp.blk1

(Niwa et al., 2004)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has leg disc phenotype, suppressible by wg^UAS.cLa/Scer\GAL4^dpp.blk1

(Niwa et al., 2004)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, suppressible by pb^UAS.A/Scer\GAL4^dpp.blk1

(Benassayag et al., 2003)

Scer\GAL4^bi-omb-Gal4, ey^UAS.cHa has eye | ectopic phenotype, suppressible by brk^UAS.cJa/Scer\GAL4^bi-omb-Gal4

(Kango-Singh et al., 2003)

Scer\GAL4^Act5C.PI, ey^UAS.cHa has eye | ectopic | somatic clone phenotype, suppressible by hh^bar3

(Kango-Singh et al., 2003)

Scer\GAL4^bi-omb-Gal4, ey^UAS.cHa has eye | ectopic phenotype, suppressible by brk^UAS.cJa/Scer\GAL4^dpp.blk1

(Kango-Singh et al., 2003)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, suppressible by Antp^UAS.cBa, Scer\GAL4^dpp.blk1

(Plaza et al., 2001)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, suppressible by Scer\GAL4^dpp.blk1/eya²

(Bonini et al., 1997)

NOT suppressed by

Statement

Reference

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, non-suppressible by eyg^M3-12/Scer\GAL4^dpp.blk1

(Jang et al., 2003)

Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype, non-suppressible by Antp^ΔHD.UAS, Scer\GAL4^dpp.blk1

(Plaza et al., 2001)

Enhancer of

Statement

Reference

ey^UAS.cHa, Scer\GAL4^ey.PH is an enhancer of eye phenotype of H^UAS.cGa, Scer\GAL4^ey.PH

(Lee et al., 2009)

ey^UAS.cHa/Scer\GAL4^ey.PH is an enhancer of eye phenotype of Scer\GAL4^ey.PH, fng^UAS.cKa

(Dominguez et al., 2004)

ey^UAS.cHa/Scer\GAL4^dpp.blk1 is an enhancer of eye disc phenotype of Scer\GAL4^dpp.blk1, eyg^UAS.lune

(Jang et al., 2003)

ey^UAS.cHa/Scer\GAL4^dpp.blk1 is an enhancer of eye | ectopic phenotype of Scer\GAL4^dpp.blk1, eyg^UAS.lune

(Jang et al., 2003)

ey^UAS.cHa/Scer\GAL4^ey.PH is an enhancer of eye phenotype of dpp^d-blk

(Curtiss and Mlodzik, 2000)

Suppressor of

Statement

Reference

Scer\GAL4^toy1/ey^UAS.cHa is a suppressor of ocellus | pharate adult stage phenotype of toy^hdl

(Jacobsson et al., 2009)

Scer\GAL4^toy1/ey^UAS.cHa is a suppressor of ocellus phenotype of toy^G7.39

(Jacobsson et al., 2009)

ey^UAS.cHa, Scer\GAL4^ey-OK107 is a suppressor of eye phenotype of Antp^UAS.cBa, Scer\GAL4^ey-OK107

(Plaza et al., 2008)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, fng^UAS.cKa

(Dominguez et al., 2004)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of eyg¹/eyg^M3-12

(Jang et al., 2003)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Scer\GAL4^ey.PH, gsb^UAS.cJa

(Jiao et al., 2001)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of Scer\GAL4^ey.PH, gsb^UAS.cJa

(Jiao et al., 2001)

ey^UAS.cHa, Scer\GAL4^dpp.blk1 is a suppressor of leg | ectopic phenotype of Antp^UAS.cBa, Scer\GAL4^dpp.blk1

(Plaza et al., 2001)

ey^UAS.cHa, Scer\GAL4^dpp.blk1 is a suppressor of antenna phenotype of Antp^UAS.cBa, Scer\GAL4^dpp.blk1

(Plaza et al., 2001)

ey^UAS.cHa/Scer\GAL4^ey.PH is a suppressor of eye phenotype of Antp^UAS.cBa, Scer\GAL4^dpp.blk1

(Plaza et al., 2001)

NOT Suppressor of

Statement

Reference

ey^UAS.cHa, Scer\GAL4^Act5C.PI is a non-suppressor of eye disc | larval stage | somatic clone - tissue specific phenotype of Mitf^UAS.cZa, Scer\GAL4^Act5C.PI

(Zhang et al., 2024)

ey^UAS.cHa/Scer\GAL4^Bx-MS1096 is a non-suppressor of wing disc | third instar larval stage phenotype of dlg1^HMS01954

(Bunker et al., 2015)

Other

Statement

Reference

Scer\GAL4^Bx-MS1096, dlg1^HMS01954, ey^UAS.cHa has wing disc | third instar larval stage phenotype

(Bunker et al., 2015)

Scer\GAL4^Act5C.PI, ey^UAS.cHa, sd^UAS.cUa has wing disc | somatic clone | third instar larval stage phenotype

(Tanaka-Matakatsu et al., 2015)

Scer\GAL4^Act5C.PI, ci^{Ce-2.UAS.Tag:HA}, ey^UAS.cHa has photoreceptor neuron | somatic clone | cell autonomous phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^Act5C.PI, ci^{Ce-2.UAS.Tag:HA}, ey^UAS.cHa has eye disc morphogenetic furrow | somatic clone | cell autonomous phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^Act5C.PI, ey^UAS.cHa, hh^UAS.cAa has eye | ectopic | somatic clone phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^Act5C.PI, ey^UAS.cHa, hh^UAS.cAa has wing disc | somatic clone phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^30A, ey^UAS.cHa, hh^UAS.cAa has eye | ectopic phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^bi-omb-Gal4, ci^UAS.Tag:HA, ey^UAS.cHa has eye | ectopic phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^Act5C.PI, dpp^UAS.cSa, ey^UAS.cHa, hh^UAS.cAa has wing disc | ectopic | somatic clone phenotype

(Kango-Singh et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, eya^UAS.cPa has photoreceptor neuron | ectopic phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, hh^UAS.cCa has wing disc phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, hh^UAS.cCa has photoreceptor neuron | ectopic phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, ey^UAS.cHa, eya^UAS.cPa, hh^UAS.cCa has wing disc phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, ey^UAS.cHa, eya^UAS.cPa, hh^UAS.cCa has photoreceptor neuron | ectopic phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa has photoreceptor neuron | ectopic phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa has wing disc | posterior phenotype

(Pappu et al., 2003)

Scer\GAL4^30A, dpp^UAS.cSa, ey^UAS.cHa, eya^UAS.cPa has wing disc phenotype

(Pappu et al., 2003)

Antp^UAS.cBa, Scer\GAL4^dpp.blk1, ey^UAS.cHa has neuron & dorsal mesothoracic disc phenotype

(Plaza et al., 2001)

N^ECN.UAS.cGa, Scer\GAL4^dpp.blk1, ey^UAS.cHa has eye | ectopic phenotype

(Kurata et al., 2000)

Scer\GAL4^dpp.blk1, ey^UAS.cHa, so¹ has leg phenotype

(Halder et al., 1998)

Scer\GAL4^dpp.blk1, ey^UAS.cHa, so¹ has wing disc phenotype

(Halder et al., 1998)

Scer\GAL4^dpp.blk1, ey^UAS.cHa, eya¹ has leg phenotype

(Halder et al., 1998)

Scer\GAL4^dpp.blk1, ey^UAS.cHa, eya^UAS.cBa has genitalia phenotype

(Bonini et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of ey^Scer\UAS.cHa in third instar larval wing discs already expressing dlg1^HMS01954 under the control of Scer\GAL4^Bx-MS1096 induces ectopic photoreceptor formation in a small proportion of cells, as compared to controls.

(Bunker et al., 2015)

Co-expression of sd^Scer\UAS.cUa with ey^Scer\UAS.cHa significantly inhibits the ability of ey^Scer\UAS.cHa to promote cell growth in the notum region. In addition, co-expression of sd^Scer\UAS.cUa with ey^Scer\UAS.cHa can also inhibit cell growth in the pouch and hinge regions as shown by decreased clone size.

(Tanaka-Matakatsu et al., 2015)

Co-expression of da^Scer\UAS.cGa results in increased size of ectopic eyes induced by Scer\GAL4^30A>ey^Scer\UAS.cHa.

Co-expression of da^{da-da.cTa.Scer\UAS} results in increased size of ectopic eyes induced by Scer\GAL4^30A>ey^Scer\UAS.cHa.

Co-expression of ato::da^Scer\UAS.cTa results in a moderate decrease in the size of ectopic eyes induced by Scer\GAL4^30A>ey^Scer\UAS.cHa.

(Tanaka-Matakatsu et al., 2014)

Co-expression of either dpp^Scer\UAS.cSa, hh^Scer\UAS.cCa or N^ICN.Scer\UAS results in enlarged wing discs containing a larger field (30-40% of disc surface area) of differentiating ectopic eye precursors compared to expression of ey^Scer\UAS.cHa alone under the control of Scer\GAL4^ap-md544.

(Nfonsam et al., 2012)

Expression of ct^Scer\UAS.cPa almost completely suppresses the ectopic eye phenotype seen in adult flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1. The photoreceptor induction seen in the wing discs is also suppressed.

Expression of hth^Scer\UAS.cPa almost completely suppresses the ectopic eye phenotype seen in adult flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1. The photoreceptor induction seen in the wing discs is also suppressed.

(Wang and Sun, 2012)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^toy1 partially suppresses the pupal lethality found in toy^hdl mutants, increasing the percentage of escapers from 3.75 to 14.1%.

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^toy1 or Scer\GAL4^toy2 suppresses the ocellar phenotype found in toy^hdl mutants in 83% of adult escapers.

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^toy1 partially suppresses the pupal lethality found in toy^hdl mutants, increasing the percentage of escapers from 5.1 to 9.5%.

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^toy1 or Scer\GAL4^toy2 suppresses the ocellar phenotype found in toy^G7.39 mutants in 85% of adult escapers.

(Jacobsson et al., 2009)

Co-expression of ey^Scer\UAS.cHa enhances the loss of eye phenotype caused by expression of H^Scer\UAS.cGa under the control of Scer\GAL4^ey.PH.

(Lee et al., 2009)

Co-expression of ey^Scer\UAS.cHa rescues eye formation in animals expressing Antp^Scer\UAS.cBa under the control of Scer\GAL4^ey-OK107.

(Plaza et al., 2008)

Co-expression of Nf-YA^{Scer\UAS.T:Ivir\HA1} partially suppresses the induction of ectopic eye structures in the wing which is caused by expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^Bx-MS1096.

(Yoshioka et al., 2007)

Scer\GAL4^ey.PH-mediated expression of ey^Scer\UAS.cHa can partially rescue the small eye phenotype seen in flies expressing fng^Scer\UAS.cKa under the control of Scer\GAL4^ey.PH in some flies, but most often enhances this phenotype and induces the expression of tiny eyes in different places of the head.

(Dominguez et al., 2004)

Coexpression of ey^Scer\UAS.cHa and tkv^CA.Scer\UAS under control of Scer\GAL4^hs.2sev results in large ectopic "eyes" (using antibodies against elav to visualize eye differentiation) in both wing and leg discs in regions far from the anterior-posterior compartment boundary. Coexpression of wg^Scer\UAS.cLa with ey^Scer\UAS.cHa, under control of Scer\GAL4^dpp.blk1, completely blocks ectopic eye formation (using antibodies against elav to visualize eye differentiation) in leg and wing discs.

(Niwa et al., 2004)

Co-expression of ey^Scer\UAS.cHa with pb^Scer\UAS.A (driven by Scer\GAL4^dpp.blk1) leads to a suppression of the ectopic eye phenotype seen in ey^Scer\UAS.cHa,Scer\GAL4^dpp.blk1 animals.

(Benassayag et al., 2003)

When ey^Scer\UAS.cHa and eyg^{Scer\UAS.lune} are driven by Scer\GAL4^dpp.blk1, the ectopic eyes produced are larger than ey^Scer\UAS.cHa or eyg^{Scer\UAS.lune} driven alone. This phenotype is more noticeable in the eye disc. The addition of ey^Scer\UAS.cHa driven by Scer\GAL4^ey.PH can partially rescue the eyg^M3-12/eyg¹ mutant eye phenotype.

(Jang et al., 2003)

When hh^Scer\UAS.cAa and ey^Scer\UAS.cHa are expressed in clones (under the control of Scer\GAL4^Act5C.PI) in the anterior compartment of the wing disc, 46% of clones cause ectopic eye formation. When hh^Scer\UAS.cAa and ey^Scer\UAS.cHa are expressed under the control of Scer\GAL4^30A in the anterior compartment of the wing disc, ectopic eye formation is seen at 100% penetrance, although the size of these ectopic eyes varies from disc to disc. When ey^Scer\UAS.cHa clones (driven by Scer\GAL4^Act5C.PI) are made in the wing disc in a hh^bar3 background no ectopic eyes are seen. When ci^{Ce-2.Scer\UAS.T:Ivir\HA1} and ey^Scer\UAS.cHa co-expressed (driven by Scer\GAL4^Act5C.PI) in clones in the wing disc, morphogenetic furrow initiation and photoreceptor differentiation are blocked within the clones. When ci^{Scer\UAS.T:Ivir\HA1} and ey^Scer\UAS.cHa are co-expressed in the wing disc (driven by Scer\GAL4^bi-omb-Gal4) ectopic eyes are induced in both anterior and posterior compartments. These eyes are larger than those seen in ey^Scer\UAS.cHa, ey^Scer\UAS.cHa animals alone. When dpp^Scer\UAS.cSa, hh^Scer\UAS.cAa and ey^Scer\UAS.cHa are co-expressed in clones (driven by Scer\GAL4^Act5C.PI), very strong overgrowth and distorted morphology is seen in the wing disc. Co-expression of dpp^Scer\UAS.cSa, hh^Scer\UAS.cAa and ey^Scer\UAS.cHa driven by Scer\GAL4^bi-omb-Gal4, causes a high larval lethality at 25^oC. The addition of brk^Scer\UAS.cJa suppresses the ectopic eye phenotype seen in ey^Scer\UAS.cHa, Scer\GAL4^bi-omb-Gal4 animals. The addition of brk^Scer\UAS.cJa suppresses the ectopic eye phenotype seen in ey^Scer\UAS.cHa, Scer\GAL4^bi-omb-Gal4 animals. The addition of brk^Scer\UAS.cJa suppresses the ectopic eye phenotype seen in ey^Scer\UAS.cHa, Scer\GAL4^dpp.blk1 animals.

(Kango-Singh et al., 2003)

When dpp^Scer\UAS.cSa and ey^Scer\UAS.cHa are driven by Scer\GAL4^30A, photoreceptor differentiation is induced in the wing disc, only in the posterior compartment. When dpp^Scer\UAS.cSa, ey^Scer\UAS.cHa and hh^Scer\UAS.cCa are driven by Scer\GAL4^30A, photoreceptor differentiation is induced in both compartments of the wing disc. When dpp^Scer\UAS.cSa, eya^Scer\UAS.cPa and ey^Scer\UAS.cHa are driven by Scer\GAL4^30A, photoreceptor differentiation is induced in both compartments of the wing disc. The addition of so^Scer\UAS.cPa increases the penetrance of this phenotype. When hh^Scer\UAS.cCa, eya^Scer\UAS.cPa and ey^Scer\UAS.cHa are driven by Scer\GAL4^30A, photoreceptor differentiation is induced in the wing disc, only in the posterior compartment. The addition of dpp^Scer\UAS.cSa and eya^Scer\UAS.cPa (driven by Scer\GAL4^ey.PB) to animals with smo^D16 clones in the eye disc, fully suppresses photoreceptor differentiation phenotype seen in eye discs. The delayed progression of the morphogenetic furrow is also rescued. If so^Scer\UAS.cPa is also added, posterior margin clones are still rescued, although ectopic anterior furrows are induced with high frequency.

(Pappu et al., 2003)

The headless phenotype caused by expression of gsb^Scer\UAS.cJa under the control of Scer\GAL4^ey.PH is partially rescued by coexpression of ey^Scer\UAS.cHa, resulting in small-eyed flies.

(Jiao et al., 2001)

Co-expression of ey^Scer\UAS.cHa and Antp^Scer\UAS.cBa when driven by Scer\GAL4^dpp.blk1 leads to a inhibition of neuronal differentiation in the wing disc. Co-expression of ey^Scer\UAS.cHa and Antp^Scer\UAS.cBa when driven by Scer\GAL4^ey.PH repsresses the Antp^Scer\UAS.cBa eye phenotypes.

(Plaza et al., 2001)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey.PH interferes with dpp^d-blk eye development to a variable extent, often resulting in smaller eyes.

(Curtiss and Mlodzik, 2000)

Flies expressing N^{ECN.Scer\UAS.cGa} and ey^Scer\UAS.cHa driven by Scer\GAL4^dpp.blk1 exhibit ectopic eyes on legs and wings in all flies.

(Kurata et al., 2000)

When ey^Scer\UAS.cHa and dac^Scer\UAS.cSa are coexpressed under the control of Scer\GAL4^30A, large ectopic eyes are seen on the wing and haltere hinges with complete penetrance. Clear ommatidial structures are seen on both the dorsal and ventral side of the wing hinge and the structure of the lens and interommatidial bristles is similar to wild-type.

(Chen et al., 1999)

Expression of ey^Scer\UAS.cHa using Scer\GAL4^dpp.blk1 in a so¹/so¹ background does not lead to the formation of ectopic eyes.

(Niimi et al., 1999)

When expression is driven by Scer\GAL4^dpp.blk1 in a so¹ or eya¹ background, no eye structures appear but legs are reduced/deformed. When expression is driven by Scer\GAL4^dpp.blk1 in a so¹ background ectopic cell death occurs in the region of the wing disc that would lead to extra eyes in a wild type background.

(Halder et al., 1998)

Flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 in a eya² background do not develop ectopic eyes. Ectopic eye formation in flies expressing ey^Scer\UAS.cHa under the control of Scer\GAL4^dpp.blk1 is greatly enhanced if the flies also carry eya^Scer\UAS.cBa; the ectopic eyes formed in flies expressing both ey^Scer\UAS.cHa and eya^Scer\UAS.cBa are larger and form with higher penetrance than in flies expressing ey^Scer\UAS.cHa alone, and eye formation occurs in the genitalia in flies expressing both ey^Scer\UAS.cHa and eya^Scer\UAS.cBa.

(Bonini et al., 1997)

Xenogenetic Interactions

Statement

Reference

The disrupted eye phenotype produced by expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^unspecified is not modified by coexpression of Hsap\HSPA1L^Scer\UAS.cWa.

(Warrick et al., 1999)

Complementation and Rescue Data

Rescues

Scer\GAL4^ey-OK107/ey^UAS.cHa rescues ey^OK107-16/ey^JD

(Clements et al., 2009)

Scer\GAL4^ey-OK107/ey^UAS.cHa rescues ey^OK107-16/ey^EH

(Clements et al., 2009)

ey^UAS.cHa/Scer\GAL4^ey.PH rescues ey^D

(Jacobsson et al., 2009)

ey^UAS.cHa rescues ey^D

(Jacobsson et al., 2009)

ey^UAS.cHa/Scer\GAL4^ey.PH rescues ey^J5.71

(Punzo et al., 2002)

Comments

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey-OK107 rescues the eye, mushroom body and central complex defects of ey^EH/ey^OK107-16 and ey^JD/ey^OK107-16 mutants.

(Clements et al., 2009)

Expression of ey^Scer\UAS.cHa under the control of Scer\GAL4^ey.PH significantly rescues the lethality seen in ey^D homozygous mutants. The flies that eclose from pupae exhibit smaller than normal heads and a majority of the compound eyes are reduced in size, while the ocelli are normal. The viability of these flies is more efficient at 18[o]C compared to 25[o]C and 29[o]C. The rescue efficiencies of flies carrying both driver and effector constructs or effector construct alone (i.e only ey^Scer\UAS.cHa) are similar.

(Jacobsson et al., 2009)

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

6294

y¹ w^*; P{UAS-ey.H}UE11

56560

w^*; wg^Sp-1/CyO; P{UAS-ey.H}3

Kyoto

108727