FlyBase Allele Report: Dmel\ey[EH]

General Information

Symbol

Dmel\ey^EH

Species

D. melanogaster

Name

FlyBase ID

FBal0147154

Feature type

allele

Associated gene

Dmel\ey

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

diepoxybutane

Nature of the Allele

Allele class

Mutagen

diepoxybutane

(Benassayag et al., 2003)

Progenitor genotype

Cytology

Description

A 6 bp sequence in exon 4 (423 to 428 in exon 4) is replaced with a single T nucleotide. This leads to a peptide truncated at amino acid 116.

(Benassayag et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

4:712,553..712,558 [+]

Comment:

A 6 bp sequence is replaced with a single T nucleotide causing a frameshift and early translation termination. The peptide truncates at amino acid 116.

Inserted_sequence:

(Benassayag et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with ey^OK107-16)

(Clements et al., 2009)

Phenotype Manifest In

adult central complex (with ey^OK107-16)

(Clements et al., 2009)

adult mushroom body (with ey^OK107-16)

(Clements et al., 2009)

eye (with ey^OK107-16)

(Clements et al., 2009)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

ey^EH is an enhancer of eye phenotype of pb^Rev3.HSPB

(Benassayag et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

ey^R

(Benassayag et al., 2003)

ey²

(Benassayag et al., 2003)

Rescued by

ey^OK107-16/ey^EH is rescued by Scer\GAL4^ey-OK107/ey^UAS.cHa

(Clements et al., 2009)

Partially rescued by

ey^OK107-16/ey^EH is partially rescued by Scer\GAL4^ey-OK107/ey^ΔHD.UAS

(Clements et al., 2009)

Not rescued by

ey^OK107-16/ey^EH is not rescued by ey^ΔPD.UAS/Scer\GAL4^ey-OK107

(Clements et al., 2009)

ey^OK107-16/ey^EH is not rescued by Scer\GAL4^ey-OK107/ey^ΔCTD.UAS

(Clements et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Allelic series based on mutant phenotype; ey¹¹ > ey^D1Da > ey^EH > ey^JD.

(Benassayag et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ey^EH

(Clements et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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