FlyBase Allele Report: Dmel\svr[1B-2-3-t2.UAS]

General Information

Symbol

Dmel\svr^{1B-2-3-t2.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0246037

Feature type

allele

Associated gene

Dmel\svr

Associated Insertion(s)

Carried in Construct

P{UAS-svr.1B-2-3-t2}

Key Links

Transgenic product class

wild_type

(Sidyelyeva et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Sidyelyeva et al., 2010)

Mutagen

in vitro construct

(Sidyelyeva et al., 2010)

Progenitor genotype

Carried in construct

P{UAS-svr.1B-2-3-t2}

Cytology

Description

UASt regulatory sequences drive expression of a 1B "long" tail-2 splice variant of svr.

(Sidyelyeva et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

svr

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

svr^{1B-2-3-t2.UAS}/Scer\GAL4^svr-PG33 partially rescues svr^PG33

(Sidyelyeva et al., 2010)

Comments

Expression of svr^{1B-2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 rescues the lethality associated with svr^PG33/Y hemizygosity. The shape of the wing is not fully rescued as a result of svr^{1B-2-3-t2.Scer\UAS} expression driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background.

Flies expressing svr^{1B-2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background show greater sensitivity in their response to ethanol than wild-type controls.

(Sidyelyeva et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

31409

w¹¹¹⁸; P{UAS-svr.1B-2-3-t2}3

31410

w¹¹¹⁸; P{UAS-svr.1B-2-3-t2}2

Notes on Origin

Discoverer