FlyBase Allele Report: Dmel\svr[PG33]

General Information

Symbol

Dmel\svr^PG33

Species

D. melanogaster

Name

FlyBase ID

FBal0129013

Feature type

allele

Associated gene

Dmel\svr

Associated Insertion(s)

P{GawB}svr^PG33

Carried in Construct

Also Known As

PG33, pg33-gal4

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Bourbon et al., 2002)

Progenitor genotype

Associated Insertion(s)

P{GawB}svr^PG33

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Sidyelyeva et al., 2010, Bourbon et al., 2002)

lethal - all die before end of larval stage | recessive

(Sidyelyeva et al., 2006)

some die during larval stage | recessive

(Sidyelyeva et al., 2006)

visible (with svr¹)

(Sidyelyeva et al., 2006)

visible (with svr^poi)

(Sidyelyeva et al., 2006)

Phenotype Manifest In

wing blade (with svr¹)

(Sidyelyeva et al., 2006)

wing blade (with svr^poi)

(Sidyelyeva et al., 2006)

wing vein (with svr¹)

(Sidyelyeva et al., 2006)

wing vein (with svr^poi)

(Sidyelyeva et al., 2006)

Detailed Description

Statement

Reference

Homozygotes die during the first or second larval instar.

(Sidyelyeva et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

svr^PG33 is rescued by svr^{1B-2-3-t1.UAS}/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

svr^PG33 is rescued by svr^{1A-2-3-t2.UAS}/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

Partially rescued by

svr^PG33 is partially rescued by svr^1B-short.UAS/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

svr^PG33 is partially rescued by svr^{1B-2-3-t2.UAS}/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

svr^PG33 is partially rescued by Scer\GAL4^svr-PG33/svr^2-3-t2.UAS

(Sidyelyeva et al., 2010)

svr^PG33 is partially rescued by svr^1B-2-t2.UAS/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

svr^PG33 is partially rescued by svr^{1B-2-1B-t2.UAS}/Scer\GAL4^svr-PG33

(Sidyelyeva et al., 2010)

svr^PG33 is partially rescued by Scer\GAL4^svr-PG33/svr^{1B-2-1A-t2.UAS}

(Sidyelyeva et al., 2010)

Not rescued by

svr^PG33 is not rescued by Scer\GAL4^svr-PG33/svr^{svr1A-short.UAS}

(Sidyelyeva et al., 2010)

Comments

Expression of svr^{1A-2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 rescues the lethality associated with svr^PG33/Y hemizygosity.

Expression of svr^{1B-2-3-t1.Scer\UAS} driven by Scer\GAL4^svr-PG33 rescues the lethality associated with svr^PG33/Y hemizygosity.

Expression of svr^{1B-2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 rescues the lethality associated with svr^PG33/Y hemizygosity. The shape of the wing is not fully rescued as a result of svr^{1B-2-3-t2.Scer\UAS} expression driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background.

Flies expressing svr^{1B-2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background show greater sensitivity in their response to ethanol than wild-type controls.

Expression of svr^{svr1A-short.Scer\UAS} driven by Scer\GAL4^svr-PG33 fails to rescue the lethality associated with svr^PG33/Y hemizygosity.

Expression of svr^{1B-2-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 partially rescues the lethality associated with svr^PG33/Y hemizygosity.

Expression of svr^{2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 partially rescues the lethality associated with svr^PG33/Y hemizygosity. The shape of the wing is not fully rescued as a result of svr^{2-3-t2.Scer\UAS} expression driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background.

Flies expressing svr^{2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background show greater sensitivity in their response to ethanol than wild-type controls.

Males expressing svr^{2-3-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background exhibit courtship suppression after training similar to that of wild-type controls indicating intact long-term memory.

Expression of svr^{1B-short.Scer\UAS} driven by Scer\GAL4^svr-PG33 partially rescues the lethality associated with svr^PG33/Y hemizygosity. The shape of the wing is not fully rescued as a result of svr^{1B-short.Scer\UAS} expression driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background.

Flies expressing svr^{1B-short.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background show greater sensitivity in their response to ethanol than wild-type controls.

Males expressing svr^{1B-short.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background exhibit courtship suppression after training similar to that of wild-type controls indicating intact long-term memory.

Flies expressing svr^{1B-short.Scer\UAS} driven by Scer\GAL4^svr-PG33 in a svr^PG33 mutant background recover more quickly from cold-induced sleep than control flies.

Expression of svr^{1B-2-1A-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 partially rescues the lethality associated with svr^PG33/Y hemizygosity.

Expression of svr^{1B-2-1B-t2.Scer\UAS} driven by Scer\GAL4^svr-PG33 partially rescues the lethality associated with svr^PG33/Y hemizygosity.

(Sidyelyeva et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

31413

y¹ P{GawB}svr^PG33 w^*/FM7h

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

svr^PG33

(Pauls et al., 2019, Sidyelyeva et al., 2010, Sidyelyeva et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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