FlyBase Allele Report: Dmel\Eph[K579M.UAS.Tag:MYC]

General Information

Symbol

Dmel\Eph^{K579M.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0246163

Feature type

allele

Associated gene

Dmel\Eph

Associated Insertion(s)

Carried in Construct

P{UAS-Eph.K759M.myc}

Key Links

Transgenic product class

missense_variant

(Scully et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Scully et al., 1999)

Mutagen

in vitro construct

(Scully et al., 1999)

Progenitor genotype

Eph^UAS.Tag:MYC

(Scully et al., 1999)

Carried in construct

P{UAS-Eph.K759M.myc}

Cytology

Description

Amino acid replacement K759M, which results in a kinase-inactive form of Eph.

(Scully et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Eph

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^A80

(Scully et al., 1999)

viable, with Scer\GAL4^elav.PLu

(Scully et al., 1999)

viable, with Scer\GAL4^elav.PLu, Scer\GAL4^sca-537.4

(Scully et al., 1999)

viable, with Scer\GAL4^elav-C155

(Scully et al., 1999)

viable, with Scer\GAL4^ftz.ng

(Scully et al., 1999)

viable, with Scer\GAL4^GMR.PF

(Scully et al., 1999)

viable, with Scer\GAL4^sca-537.4

(Scully et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Eph^{K579M.Scer\UAS.T:Hsap\MYC} under the control of any one of Scer\GAL4^elav-C155, Scer\GAL4^sca-537.4, Scer\GAL4^elav.PLu, Scer\GAL4^ftz.ng, Scer\GAL4^A80 or Scer\GAL4^GMR.PF does not result in a mutant phenotype.

Expression of Eph^{K579M.Scer\UAS.T:Hsap\MYC} under the simultaneous control of Scer\GAL4^sca-537.4 and Scer\GAL4^elav.PLu does not result in a mutant phenotype.

(Scully et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Eph^{K579M.Scer\UAS.T:Hsap\MYC}

Eph^{K579M.UAS.Tag:MYC}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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