FlyBase Allele Report: Dmel\Wnt4[UAS.WT]

General Information

Symbol

Dmel\Wnt4^UAS.WT

Species

D. melanogaster

Name

FlyBase ID

FBal0246429

Feature type

allele

Associated gene

Dmel\Wnt4

Associated Insertion(s)

Carried in Construct

P{UAS-Wnt4.WT}

Key Links

Transgenic product class

wild_type

(Sato et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Sato et al., 2006)

Mutagen

in vitro construct

(Sato et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-Wnt4.WT}

Cytology

Description

UAS regulatory sequences drive expression of Wnt4 coding sequences.

(Sato et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Wnt4

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^NP6099

(Sato et al., 2006)

Phenotype Manifest In

eye photoreceptor cell, with Scer\GAL4^NP6099

(Sato et al., 2006)

lamina, with Scer\GAL4^NP6099

(Sato et al., 2006)

neuron, with Scer\GAL4^NP6099

(Sato et al., 2006)

Detailed Description

Statement

Reference

Expression of Wnt4^Scer\UAS.cSa in the dorsal and ventral lamina under the control of Scer\GAL4^NP6099 results in axonal mis-projection. Ventral axons project to the ectopic source of Wnt4 in the dorsal lamina and dorsal axons project to the ventral lamina with a less expressivity, suggesting that dorsal axons are less sensitive to Wnt4 than ventral axons are.

(Sato et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Scer\GAL4^C587/Wnt4^UAS.WT is a non-suppressor of decreased cell number | oogenesis phenotype of Scer\GAL4^C587, sov^RNAi.UAS.3-2

(Jankovics et al., 2018)

Scer\GAL4^C587/Wnt4^UAS.WT is a non-suppressor of neoplasia | oogenesis phenotype of Scer\GAL4^C587, sov^RNAi.UAS.3-2

(Jankovics et al., 2018)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^C587/Wnt4^UAS.WT is a non-suppressor of cystoblast phenotype of Scer\GAL4^C587, sov^RNAi.UAS.3-2

(Jankovics et al., 2018)

Scer\GAL4^C587/Wnt4^UAS.WT is a non-suppressor of escort cell phenotype of Scer\GAL4^C587, sov^RNAi.UAS.3-2

(Jankovics et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Wnt4^Scer\UAS.WT

Wnt4^UAS.WT

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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