FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Raffl.UAS
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General Information
Symbol
Dmel\Raffl.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0246433
Feature type
allele
Associated gene
Dmel\Raf
Associated Insertion(s)
Carried in Construct
P{UAS-Raf.fl}
Key Links
Transgenic product class
wild_type
(Moressis et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Moressis et al., 2009)
Mutagen
in vitro construct
(Moressis et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Raf.fl}
Cytology
Description

UASt regulatory sequences drive expression of full-length Raf sequences.

(Moressis et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Raf
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4c747/Raffl.UAS is a suppressor of abnormal learning phenotype of drke0A

      (Moressis et al., 2009)
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4c747/Raffl.UAS is a non-suppressor of abnormal memory phenotype of drkΔP24

      (Moressis et al., 2009)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of phlfl.Scer\UAS in the mushroom bodies under the control of Scer\GAL4c747 improves immediate performance of drkΔP24 heterozygotes significantly, but not to the level of wild-type.

      Expression of phlfl.Scer\UAS under the control of Scer\GAL4c747 does not rescue 90 minute memory in drkΔP24/+ animals.

      Expression of phlfl.Scer\UAS under the control of Scer\GAL4c747 results in full reversal of the learning deficit of drke0A heterozygotes.

      (Moressis et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DRAFwt
      (Pfeifle et al., 2019)
      Raffl.Scer\UAS
      Raffl.UAS
      phlfl.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)