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General Information
Symbol
Dmel\HDAC1UAS.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0246491
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Rpd3-V5
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of HDAC1 which is tagged with Tag:V5.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing HDAC1Scer\UAS.T:SV5\V5 under the control of Scer\GAL4fat exhibit significantly shorter survival time under starvation stress, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Rpd3Scer\UAS.T:SV5\V5 under the control of Scer\GAL4GH146 in DL1 projection neuron clones which are mutant for pros38 does not rescue the dendrite mistargeting or axon overbranching defects seen in these mutant clones.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of Rpd3Scer\UAS.T:SV5\V5 under the control of Scer\GAL4GH146 in single-cell DL1 projection neuron clones which are mutant for one of Rpd312-37, Rpd3303 or Rpd3def24 significantly rescues the dendrite mistargeting defects seen in these clones.

Expression of Rpd3Scer\UAS.T:SV5\V5 under the control of Scer\GAL4GH146 in single-cell DL1 projection neuron clones is sufficient to rescue the axon overbranching phenotype in the lateral horn which is seen in these clones.

Expression of Rpd3Scer\UAS.T:SV5\V5 under the control of Scer\GAL4GH146 in projection neuron neuroblast clones which are homozygous for Rpd312-37 does not rescue the reduced cell number seen in these clones.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
HDAC1Scer/UAS:SV5/V5
HDAC1Scer\UAS.T:SV5\V5
HDAC1UAS.Tag:V5
Rpd3Scer\UAS.T:SV5\V5
Name Synonyms
Secondary FlyBase IDs
    References (4)