FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\HDAC3UAS.Tag:FLAG
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General Information
Symbol
Dmel\HDAC3UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0246493
Feature type
allele
Associated gene
Dmel\HDAC3
Associated Insertion(s)
Carried in Construct
P{UAS-HDAC3.3xFLAG}
Also Known As
UAS-HDAC3
Key Links
Transgenic product class
wild_type
(Tea et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tea et al., 2010)
Mutagen
in vitro construct
(Tea et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-HDAC3.3xFLAG}
Cytology
Description

UAS regulatory sequences drive expression of HDAC3 which is tagged at the C-terminal end with three copies of Tag:FLAG.

(Tea et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
HDAC3
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      PBac{GH146-GAL4.B}-marked anterodorsal single cell clones in Snr16C mutants (that also express Hdac3Scer\UAS.T:Zzzz\FLAG) display mistargeting to non-stereotyped glomeruli throughout the antennal lobe. PBac{GH146-GAL4.B}-marked neuroblast clones in Snr101319 mutants (that also express Hdac3Scer\UAS.T:Zzzz\FLAG) display phenotypes where dendrites make small, meandering projections throughout the antennal lobe and exhibit extremely perturbed cell morphology.

      (Tea and Luo, 2011)

      The dendrite targeting and axon arborisation defects seen in Rpd312-37 single-cell DL1 projection neuron clones are not rescued by expression in the mutant clone of Hdac3Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GH146.

      The reduction in cell number seen in Rpd312-37 projection neuron neuroblast clones is not rescued by expression in the mutant clone of Hdac3Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GH146.

      (Tea et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      HDAC3Scer\UAS.T:Zzzz\FLAG
      HDAC3UAS.Tag:FLAG
      Hdac3Scer\UAS.T:Zzzz\FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (4)