FB2026_02 , released June 18, 2026
Allele: Dmel\sggtwkr
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General Information
Symbol
Dmel\sggtwkr
Species
D. melanogaster
Name
FlyBase ID
FBal0246528
Feature type
allele
Associated gene
Dmel\sgg
Associated Insertion(s)
P{GawB}sggtwkr
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}sggtwkr
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        After exposure to four pulses of ethanol vapor delivered at 6 minute intervals, wild-type flies habituate to 43% of naive response levels, whereas sggtwkr mutants display a reduced acquisition of habituation but a normal discrimination between divergent stimuli.

        sggtwkr mutants exhibit a significant lengthening of circadian period. sggtwkr heterozygotes show a normal period length.

        (Wolf et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        With respect to circadian period length, the following alleles can be ranked from longest to shortest: sggEP1576 = sggtwkr/+ = sgg1/sggEP1576 < sggtwkr/sggtwkr < sgg1/sggtwkr.

        (Wolf et al., 2007)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        sggtwkr
        Name Synonyms
        Secondary FlyBase IDs
          References (1)