FB2026_02 , released June 18, 2026
Allele: Dmel\bazX-82
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General Information
Symbol
Dmel\bazX-82
Species
D. melanogaster
Name
FlyBase ID
FBal0246566
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: ?1192term.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Nucleotide change:

    A17192710T

    Amino acid change:

    K1192term | baz-PA; K1213term | baz-PB; K1192term | baz-PC; K1213term | baz-PD

    Reported amino acid change:

    ?1192term

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Embryos derived from females carrying homozygous germline clones develop an average of 5.9 of the wild-type 8 abdominal segments. Approximately 40% of the embryos have defects in dorsoventral patterning, including a single dorsal appendage or lack of dorsal appendage material.

    17% of embryos derived from homozygous female germline clones initiate the process of pole cell formation, with the budding of plasma membrane around germ plasm-associated nuclei, at ectopic locations. Unlike wild-type pole buds, these ectopic buds do not progress to form cells.

    Nuclear migration is aberrant or fails in approximately 50% of mutant oocytes and microtubule organisation and polarity is altered in mutant stage 9 oocytes compared to wild type. Cytoplasmic streaming fails to occur in approximately 75% of late stage mutant oocytes.

    The position of the oocyte nucleus is normal in egg chambers containing large follicle cell clones that encompass the posterior follicle cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Fails to complement
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    Separable from: an unlinked lethal mutation on the chromosome.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (1)