FlyBase Allele Report: Dmel\Usp7[Δ35]

General Information

Symbol

Dmel\Usp7^Δ35

Species

D. melanogaster

Name

FlyBase ID

FBal0247476

Feature type

allele

Associated gene

Dmel\Usp7

Associated Insertion(s)

P{?SUPor-P}Usp7^Δ35

Carried in Construct

Key Links

Allele class

hypomorphic allele

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele

(van der Knaap et al., 2010)

Mutagen

P-element activity

(van der Knaap et al., 2010)

Progenitor genotype

P{SUPor-P}Usp7^KG06814

(van der Knaap et al., 2010)

Associated Insertion(s)

P{?SUPor-P}Usp7^Δ35

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of the 5' untranslated region and removes coding sequence for the first 23 amino acid residues of Usp7. 24bp of the original insertion remain.

(van der Knaap et al., 2010)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(van der Knaap et al., 2010)

visible

(van der Knaap et al., 2010)

Phenotype Manifest In

wing

(van der Knaap et al., 2010)

Detailed Description

Statement

Reference

Hemizygous males have a "held-out wing" phenotype.

(van der Knaap et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Usp7^Δ35 has visible phenotype, enhanceable by bur[+]/bur^k07130

(van der Knaap et al., 2010)

Usp7^Δ35 has visible phenotype, enhanceable by bur^e10/bur[+]

(van der Knaap et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Usp7^Δ35 has wing phenotype, enhanceable by bur[+]/bur^k07130

(van der Knaap et al., 2010)

Usp7^Δ35 has wing phenotype, enhanceable by bur^e10/bur[+]

(van der Knaap et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for either bur^k07130 or bur^e10 enhances the "held-out wing" phenotype of Usp7^Δ35 hemizygotes.

(van der Knaap et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Usp7^Δ35

(Derkacheva et al., 2016, van der Knaap et al., 2010)

Usp^Δ35

(van der Knaap et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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