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General Information
Symbol
Dmel\GaleΔy
Species
D. melanogaster
Name
FlyBase ID
FBal0247660
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dGALEΔy
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision allele generated by mobilizing P{EPgy2}GaleEY22205, creating a 1339 bp deletion that includes the first coding exon.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Some zygotic GaleΔy/Galef00624 animals die as embryos, whereas others survive to first-second larval instar stages. Surviving L1 and L2 larvae are abnormally small and lethargic.

GaleΔy/Galef00624 zygotic animals derived from Galef00624 germline clones die uniformly in late embryogenesis displaying no morphological defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of Hsap\GALEScer\UAS.cSa using either Scer\GAL4arm.PS or Scer\GAL4Act5C.PI rescues the lethality of GaleΔy/Galef00624 animals. Rescued animals are viable, fertile, and appear morphologically normal.

Expression of Hsap\GALEScer\UAS.cSa using Scer\GAL4drm.7.1 partially rescues the lethality of GaleΔy/Galef00624 animals, whereas use of Scer\GAL4elav-C155 or Scer\GAL4c754 is completely insufficient to rescue or delay lethality of this genotype.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)