FB2026_02 , released June 18, 2026
Allele: Dmel\fweUASp.ubi
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General Information
Symbol
Dmel\fweUASp.ubi
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Rhiner
FlyBase ID
FBal0247684
Feature type
allele
Associated gene
Dmel\fwe
Associated Insertion(s)
Carried in Construct
P{UASp-fwe.ubi}
Key Links
Transgenic product class
wild_type
(Rhiner et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rhiner et al., 2010)
Mutagen
in vitro construct
(Rhiner et al., 2010)
Progenitor genotype
Carried in construct
P{UASp-fwe.ubi}
Cytology
Description

UASp regulatory sequences drive expression of the "ubi" isoform of fwe.

(Rhiner et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
fwe
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of fweScer\UAS.P\T.ubi in photoreceptor neurons under the control of Scer\GAL4elav.PU does not suppress the physiological cell death seen at the periphery of the pupal retina.

      Expressing fweScer\UAS.P\T.ubi under the control of Scer\GAL4GMR.PF (but restricting expression in the neuronal cells using Scer\GAL80elav.PU) does not suppress the physiological cell death seen at the periphery of the pupal retina.

      Expressing fweScer\UAS.P\T.ubi in primary pigment cells and cone cells under the control of Scer\GAL4wg.PU does not suppress the physiological cell death seen at the periphery of the pupal retina.

      (Merino et al., 2013)

      Overexpression of fweScer\UAS.cRa driven by Scer\GAL4Act5C.PI in cell clones does not trigger apoptosis in the wing imaginal disc epithelium.

      (Rhiner et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      fweUASp.ubi rescues fwee202

      (Rhiner et al., 2010)
      Comments

      Expression of fweScer\UAS.cRa under the control of Scer\GAL4αTub84B.PL in homozygous fwee202 mutant cell clones rescues the cell death phenotype associated with fwee202.

      (Rhiner et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      fweScer\UAS.P\T.ubi
      fweScer\UAS.cRa
      fweUASp.ubi
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Rhiner
      Secondary FlyBase IDs
        References (4)