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General Information
Symbol
Dmel\fwee202
Species
D. melanogaster
Name
FlyBase ID
FBal0247696
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

Imprecise excision of P{EPgy2}fwe[EY08496], deleting 1.0 kb of DNA that spans the 5' UTR and first 2 coding exons of fwe.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of P{EPgy2}fweEY08496 resulting in the deletion of the 5' UTR and the first two exons of fwe, including the start ATG in exon 1.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous fwee202 mutant cell clones survive initially in the wing imaginal disc epithelium, but they are gradually eliminated due to apoptosis.

Posterior compartments of wing imaginal discs that are formed entirely by homozygous fwee202 mutant cell clones reach their final size before the neighbouring anterior compartment composed of RpL19unspecified/+ cells. The fwee202 mutant cell clones exhibit massive signs of apoptosis.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Not rescued by
Comments

Expression of fweScer\UAS.cRa under the control of Scer\GAL4αTub84B.PL in homozygous fwee202 mutant cell clones restores the survival of fwee202 mutant cells.

Expression of fweScer\UAS.cRb under the control of Scer\GAL4αTub84B.PL in homozygous fwee202 mutant cell clones does not restore the survival of fwee202 mutant cells.

Expression of fweScer\UAS.cRc under the control of Scer\GAL4αTub84B.PL in homozygous fwee202 mutant cell clones does not restore the survival of fwee202 mutant cells.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)