FB2026_02 , released June 18, 2026
Allele: Dmel\crbGFP-A
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General Information
Symbol
Dmel\crbGFP-A
Species
D. melanogaster
Name
FlyBase ID
FBal0247913
Feature type
allele
Associated gene
Dmel\crb
Associated Insertion(s)
TI{TI}crbGFP-A
Carried in Construct
Also Known As
crb::GFP-A, Crumbs-GFP, Crb::GFP, Crumbs::GFP, Crb-GFP, crumbs-GFPA
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
recombination
(Huang et al., 2009)
Progenitor genotype
crbGX24w-
(Huang et al., 2009)
Associated Insertion(s)
TI{TI}crbGFP-A
Cytology
Description

crb tagged at amino acid position 2121 with GFP has been knocked in to a founder knockout line containing a attP site (crbGX24w-).

(Huang et al., 2009)
Allele components
Component
Use(s)
Tagged with
GFP
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      embryonic/larval tracheal section

      Comment: apical epithelial surface and lumen

      (Chen and Krasnow, 2014)
      tracheal lumen
      (Chen and Krasnow, 2014)
      Additional Information
      Statement
      Reference

      The Crumbs-GFP fusion protein labels the apical epithelial surface and tracheal lumen. Localizes on apical tracheal progenitor cell surfaces.

      (Chen and Krasnow, 2014)
       
      Marker for
      tracheal lumen
      (Chen and Krasnow, 2014)
      Reflects expression of
      crb
      (Chen and Krasnow, 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (9)
      Reported As
      Symbol Synonym
      Crb-GFP
      (Bell et al., 2015)
      Crb::GFP-A
      (Huang et al., 2011, Huang et al., 2009)
      Crumbs-GFP
      (Song et al., 2013, Wang et al., 2012)
      Crumbs::GFP
      (Schottenfeld-Roames and Ghabrial, 2012)
      crb::GFP-A
      (Caussinus et al., 2011)
      crb:GFP-A
      (Mishra et al., 2012)
      crbGFP-A
      crbKI.A.T:Avic\GFP
      crumbs-GFPA
      (Song et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (19)