FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lsd-1+t3.5
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General Information
Symbol
Dmel\Lsd-1+t3.5
Species
D. melanogaster
Name
FlyBase ID
FBal0247950
Feature type
allele
Associated gene
Dmel\Lsd-1
Associated Insertion(s)
Carried in Construct
P{Lsd-1.3.5}
Key Links
Genomic Maps

Transgenic product class
missense_variant
(Beller et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Beller et al., 2010)
Mutagen
in vitro construct
(Beller et al., 2010)
Progenitor genotype
Carried in construct
P{Lsd-1.3.5}
Cytology
Description

Genomic fragment consisting of nucleotides 3R:19589032..19592544 (release 5 of the genome assembly), which contains Lsd-1. This rescue construct contains two amino acid substitutions compared to the annotated Lsd-1-PC isoform (P238H and L337P).

(Beller et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
Lsd-1
Encoded product / tool
Lsd-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:23,763,310..23,766,822 [+]
Comment:

3.5 kb Lsd-1 rescue fragment boundaries from reported R5 coordinates.

(Beller et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Lsd-1+t3.5 rescues Lsd-11

      (Beller et al., 2010)
      Comments

      Lsd-1+t3.5 rescues the increased body fat content of Lsd-11 flies.

      One copy of Lsd-1+t3.5 partially rescues the increased starvation resistance seen in Lsd-11 flies.

      (Beller et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Lsd-1+t3.5
      Name Synonyms
      Secondary FlyBase IDs
        References (2)