FlyBase Allele Report: Dmel\Rho1[HMS00375]

General Information

Symbol

Dmel\Rho1^HMS00375

Species

D. melanogaster

Name

FlyBase ID

FBal0248139

Feature type

allele

Associated gene

Dmel\Rho1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00375}

Also Known As

HMS00375

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00375}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00375

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rho1^HMS00375, Scer\GAL4^hs.2sev is a suppressor of increased cell death phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

Rho1^HMS00375, Scer\GAL4^Cg.PA is a suppressor of fat cell | third instar larval stage phenotype of Scer\GAL4^Cg.PA, shot^GL01286

(Sun et al., 2019)

Rho1^HMS00375, Scer\GAL4^Cg.PA is a suppressor of endoplasmic reticulum | third instar larval stage phenotype of Scer\GAL4^Cg.PA, shot^GL01286

(Sun et al., 2019)

Rho1^HMS00375, Scer\GAL4^Cg.PA is a suppressor of nucleus | third instar larval stage phenotype of Scer\GAL4^Cg.PA, shot^GL01286

(Sun et al., 2019)

Rho1^HMS00375, Scer\GAL4^hs.2sev is a suppressor of eye phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

A Rho1^HMS00375 background rescues the reduced adult eye size phenotype found in Scer\GAL4^hs.2sev->Mmus\Gria1^Lc.Scer\UAS flies.

(Yang et al., 2013)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

32383

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00375}attP2/TM3, Sb¹

NIG-Fly

HMS00375

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00375}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Rho1^HMS00375

(Zheng et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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