FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wrdUAS.Tag:FLAG
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General Information
Symbol
Dmel\wrdUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0248459
Feature type
allele
Associated gene
Dmel\wrd
Associated Insertion(s)
Carried in Construct
P{UAS-wrd.FLAG}
Key Links
Transgenic product class
wild_type
(Hahn et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hahn et al., 2010)
Mutagen
in vitro construct
(Hahn et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-wrd.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of wrd tagged with Tag:FLAG.

(Hahn et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
wrd
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Parkinson's disease 8
      modeled by Hsap\LRRK2G2019S.UAS.Tag:MYC
      (Sim et al., 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of PP2A-B'Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4en.PU results in lethality. Over expression of a weaker insertion of PP2A-B'Scer\UAS.T:Zzzz\FLAG gives viable adults with a reduced posterior wing compartment.

      Expression of PP2A-B'Scer\UAS.T:Zzzz\FLAG in the head and eye under the control of Scer\GAL4ey.PH results in a reduction in tissue size.

      (Hahn et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      wrdUAS.Tag:FLAG/Scer\GAL4hs.PB rescues wrdKO1

      (Hahn et al., 2010)
      Comments

      Expression of PP2A-B'Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4hs.PB rescues the shorter life-span and lean body composition of PP2A-B'KO1 mutant flies.

      (Hahn et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PP2A-B'Scer\UAS.T:Zzzz\FLAG
      wrdScer\UAS.T:Zzzz\FLAG
      wrdUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)