FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CtBPTag:FLAG
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General Information
Symbol
Dmel\CtBPTag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0248951
Feature type
allele
Associated gene
Dmel\CtBP
Associated Insertion(s)
Carried in Construct
P{CtBP.WT.FLAG}
Key Links
Transgenic product class
genomic_DNA
(Zhang and Arnosti, 2011)
wild_type
(Zhang and Arnosti, 2011)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Zhang and Arnosti, 2011)
wild_type
(Zhang and Arnosti, 2011)
Mutagen
in vitro construct
(Zhang and Arnosti, 2011)
Progenitor genotype
Carried in construct
P{CtBP.WT.FLAG}
Cytology
Description

A 16-kb genomic fragment containing 8 kb upstream and 1 kb downstream of the CtBP primary transcript. The construct incorporates a C-terminal tandem 2xTag:FLAG epitope tag.

(Zhang and Arnosti, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
CtBP
Encoded product / tool
CtBP
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      CtBPTag:FLAG is a suppressor | partially of visible | adult stage phenotype of CtBP87De-10, Scer\GAL4rn-GAL4-5, egrUAS.cUa

      (Worley et al., 2018)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      CtBPTag:FLAG is a suppressor | partially of wing | ectopic phenotype of CtBP87De-10, Scer\GAL4rn-GAL4-5, egrUAS.cUa

      (Worley et al., 2018)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of egrUAS.cUa (under the control of Scer\GAL4rn-GAL4-5 with tub-Gal80[ts] restricting expression to third instar larvae) and CtBPTag:FLAG does not lead to ectopic wings compared to controls.

      (Worley et al., 2018)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      CtBPTag:FLAG partially rescues CtBP03463/CtBP87De-10

      (Zhang and Arnosti, 2011)

      CtBPTag:FLAG partially rescues Df(3R)Exel8157/CtBP87De-10

      (Zhang and Arnosti, 2011)

      CtBPTag:FLAG partially rescues Df(3R)BSC615/CtBP87De-10

      (Zhang and Arnosti, 2011)

      CtBPTag:FLAG partially rescues CtBP03463

      (Zhang and Arnosti, 2011)
      Comments

      A considerable number of adult flies survive despite being homozygous for CtBP03463 in the presence of CtBPT:Zzzz\FLAG. The hatch rate of maternally rescued CtBP03463 embryos is similar to that of wild-type embryos.

      Homozygous CtBP03463 mutant adults zygotic-rescued by CtBPT:Zzzz\FLAG display a variety of wing defects, ranging from mildly curly wings to blistered wing phenotypes, and, in some cases, severely reduced wings.

      (Zhang and Arnosti, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CtBPT:Zzzz\FLAG
      CtBPTag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)