FB2026_02 , released June 18, 2026
Allele: Dmel\pleΔ2g
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General Information
Symbol
Dmel\pleΔ2g
Species
D. melanogaster
Name
FlyBase ID
FBal0249082
Feature type
allele
Associated gene
Dmel\ple
Associated Insertion(s)
Carried in Construct
P{pleΔ2g}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Friggi-Grelin et al., 2003)
Progenitor genotype
ple+t10.988
(Friggi-Grelin et al., 2003)
Carried in construct
P{pleΔ2g}
Cytology
Description

The ple genomic region, including 4.1kb of upstream promoter sequences is cloned (to generate ple+t10.988) and then intronic sequences i[[2]], i[[3]], and i[[4]] are removed.

(Friggi-Grelin et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
ple
Encoded product / tool
ple
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      pleΔ2g rescues ple2

      (Friggi-Grelin et al., 2003)
      Comments

      The presence of pleΔ2g transgene either significantly rescues ple2 embryonic lethality or full pupal rescue. Few rescued adults are observed with pleΔ2g, possibly because of a limiting expression level of the transgene at this stage.

      (Friggi-Grelin et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pleΔ2g
      Name Synonyms
      Secondary FlyBase IDs
        References (1)