FB2026_02 , released June 18, 2026
Allele: Dmel\Pgant3m2
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General Information
Symbol
Dmel\Pgant3m2
Species
D. melanogaster
Name
FlyBase ID
FBal0249311
Feature type
allele
Associated gene
Dmel\Pgant3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Zhang et al., 2010)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G?A.

(Zhang et al., 2010)

Amino acid replacement: W609term.

(Zhang et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:7,058,393..7,058,393 [-]
Nucleotide change:

G7058393A

Reported nucleotide change:

G?A

Amino acid change:

W609term | pgant3-PA

Reported amino acid change:

W609term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Zhang et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      pgant3m2/Df(2R)Exel6283, pgant3m1/pgant3m2 and pgant3m2/pgant3c01318 flies have a blistered wing phenotype.

      (Zhang et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      pgant3[+]/Pgant3m2 is an enhancer of visible | recessive phenotype of if3

      (Zhang et al., 2010)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      pgant3[+]/Pgant3m2 is an enhancer of wing blade phenotype of if3

      (Zhang et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the wing blistering phenotype seen in if3/Y flies (17%) is increased if they are also heterozygous for pgant3m2 (52% penetrance).

      (Zhang et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pgant3m2
      pgant3m2
      (Zhang et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)