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General Information
Symbol
Scer\GAL4GMR47E12
Species
S. cerevisiae
Name
FlyBase ID
FBal0252861
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 2012 base pair fragment from the flanking non-coding or intronic region of CG31646 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Use of Scer\GAL80ChAT.3.3P restricts expression of a UAS target to the CLI1 and CLI2 neurons by inhibiting Scer\GAL4GMR47E12 expression in other interneurons. Use of Scer\GAL80tsh-GAL80 restricts expression of a UAS target to the CLI1 neurons by inhibiting Scer\GAL4GMR47E12 expression in other interneurons.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 660 nm (red) light) of a subset of Scer\GAL4GMR47E12 cells (expression restricted using Scer\GAL80ChAT.3.3P, or the combination of Scer\GAL80ChAT.3.3P and Scer\GAL80tsh-GAL80) halts forwards locomotion and significantly induces contraction of the abdomen, compared to controls. In the case of the subset of Scer\GAL4GMR47E12 cells activated when only Scer\GAL80ChAT.3.3P is also present, neuromere-specific activation results in segment-specific contraction of body wall muscles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4GMR47E12
Name Synonyms
Secondary FlyBase IDs
    References (3)